1-Chloro-1,1-difluoroethane
1-Chloro-1,1-difluoroethane (CAS 75-68-3), also known as HCFC-142b, is a halogenated hydrocarbon with the molecular formula CH3CF2Cl and a molecular weight of 100.50 g/mol. This compound serves as a valuable reagent in chemical synthesis. It is typically supplied at a purity of 98%. As a component in specialty gases and synthetic reagents, it finds application in various laboratory and industrial processes.
- IUPAC
- HCFC-142b
- Synonyms
- CH3CF2ClHCFC-142b

Chemical Synthesis
1-Chloro-1,1-difluoroethane is employed as a building block or reagent in the synthesis of complex organic molecules. Its unique halogenation pattern makes it suitable for introducing specific fluorinated functionalities into target compounds.
Specialty Gases
This compound is utilised as a component in specialty gas mixtures for various industrial and research applications. Its properties may be advantageous in specific gas phase reactions or analytical standards.
Synthetic Reagents
As a synthetic reagent, 1-Chloro-1,1-difluoroethane can participate in a range of chemical transformations. Its reactivity is influenced by the presence of both chlorine and fluorine atoms on the same carbon.
| Molecular weight | 100.50 |
|---|---|
| Linear formula | CH3CF2Cl |
| Assay | 98% |
| Boiling point | −10 °C(lit.) |
| Vapour pressure | 2196 mmHg (21 °C) |
| Vapour density | 3.49 (vs air) |
| Autoignition temp | 1169 °F |
| Melting point | −131 °C(lit.) |
| Application | Please view www.aldrich.com/epaods regarding the EPA′s request for application information of Ozone Depleting Substances |


Hazard statements
- H220Extremely flammable gas
- H280Contains gas under pressure; may explode if heated
- H420
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P410Protect from sunlight
| Protective equipment | Eyeshields, Faceshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Transport (UN / ADR) | UN 2517 2.1 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F+,N |
| Risk statements (R) | 12-59 |
| Safety statements (S) | 38-59 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Chloro-1,1-difluoroethane used for?
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1-Chloro-1,1-difluoroethane is primarily used in chemical synthesis, as a component in specialty gases, and as a synthetic reagent. For information regarding the EPA's request for application data on Ozone Depleting Substances, please refer to www.aldrich.com/epaods.
What are the CAS number and formula for 1-Chloro-1,1-difluoroethane?
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The CAS number for 1-Chloro-1,1-difluoroethane is 75-68-3, and its linear formula is CH3CF2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Chloro-1,1-difluoroethane with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should 1-Chloro-1,1-difluoroethane be handled safely?
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1-Chloro-1,1-difluoroethane is highly flammable and may cause an allergic skin reaction. It is also a gas under pressure and can cause cold burns or frozen tissue. It is harmful to the public and the environment as it may cause widespread and long-term damage to the environment. Always use appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Store away from heat and open flames.
How is 1-Chloro-1,1-difluoroethane packed and exported?
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1-Chloro-1,1-difluoroethane is supplied according to UN 2517 2.1 regulations, indicating it is a flammable gas. TSS exports chemicals globally, adhering to all relevant transportation and customs regulations for hazardous materials.
How can I request a sample or quote for 1-Chloro-1,1-difluoroethane?
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To request a sample or a quote for 1-Chloro-1,1-difluoroethane, please contact our sales team through the website or by phone. Please specify the quantity and any delivery requirements.
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