1-Aza-18-crown-6
1-Aza-18-crown-6 (CAS: 33941-15-0, C12H25NO5) is a cyclic polyether with a nitrogen atom incorporated into the ring structure, contributing to its unique complexation properties. This compound functions effectively as a chelating agent, forming stable complexes with various metal cations. Its primary applications lie in chemical synthesis and research, where it serves as a specialized reagent. With a molecular weight of 263.33, it is supplied by TSS at a purity of 95%.
- IUPAC
- 1,4,7,10,13-Pentaoxa-16-azacyclooctadecane
- Synonyms
- 1,4,7,10-Pentaoxa-13-azacyclooctadecane1,4,7,10,13-Pentaoxa-16-azacyclooctadecane

Metal Ion Complexation
1-Aza-18-crown-6 is employed for its ability to selectively bind and sequester metal ions. This property is valuable in separation processes and in influencing the reactivity of metal cations in solution.
Chemical Synthesis
As a crown ether derivative, this compound can act as a phase-transfer catalyst or a reagent in organic synthesis. It facilitates reactions involving cations by solvating them, enhancing their solubility in organic solvents.
Research and Development
In laboratory settings, 1-Aza-18-crown-6 is used in studies exploring host-guest chemistry and the development of new materials or analytical methods involving cation recognition.
| Molecular weight | 263.33 |
|---|---|
| Empirical formula | C12H25NO5 |
| Assay | 95% |
| Melting point | 46-49 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Aza-18-crown-6 used for?
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1-Aza-18-crown-6 is primarily used for its chelating and complexation abilities, particularly with metal ions, and serves as a reagent in chemical synthesis and research.
What are the CAS number and formula for 1-Aza-18-crown-6?
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The CAS number is 33941-15-0 and the empirical formula is C12H25NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Aza-18-crown-6 with an assay of 95%. This product is not represented as USP, BP, or EP grade.
How should 1-Aza-18-crown-6 be handled?
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Handle 1-Aza-18-crown-6 with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, as it may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is 1-Aza-18-crown-6 available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-Aza-18-crown-6, available for international shipment.
How can I request a quote or sample?
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To request a quote or sample of 1-Aza-18-crown-6, please contact our sales department through the TSS website or by phone.
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