1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol
1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol (CAS 51064-65-4) is a specialised carbohydrate derivative with a molecular weight of 470.56 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the fields of carbohydrate chemistry and chemical biology. Its well-defined structure and tosylate leaving groups make it suitable for various synthetic transformations and the construction of complex molecular architectures.
- IUPAC
- (+)-2,3-O-Isopropylidene-1,4-di-O-tosyl-D-threitol,(+)-2,3-O-Isopropylidene-D-threitol 1,4-ditosylate,(4R,5R)-4,5-Bis(tosyloxymethyl)-2,2-dimethyl-1,3-dioxolane,2,3-Isopropylidene-D-threitol 1,4-ditosylate
- Synonyms
- 51064-65-4, C21H26O8S2, (+)-2,3-O-Isopropylidene-1,4-di-O-tosyl-D-threitol,(+)-2,3-O-Isopropylidene-D-threitol 1,4-ditosylate,(4R,5R)-4,5-Bis(tosyloxymethyl)-2,2-dimethyl-1,3-dioxolane,2,3-Isopropylidene-D-threitol 1,4-ditosylate
Chiral Building Block in Organic Synthesis
This compound is used as a chiral synthon for the preparation of complex organic molecules. The presence of tosylate groups allows for facile nucleophilic substitution reactions, enabling the introduction of diverse functionalities.
Carbohydrate Derivative Synthesis
It functions as a key intermediate in the synthesis of modified carbohydrates and carbohydrate-like structures. The isopropylidene acetal protects the diol, allowing selective tosylation of the primary hydroxyl groups.
Research and Development
Utilised in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities. Its specific stereochemistry is crucial for applications requiring enantiopure compounds.
| Molecular weight | 470.56 |
|---|---|
| Empirical formula | C21H26O8S2 |
| Assay | 97% |
| Optical activity | [α]20/D +12.1°, c = 8.8 in chloroform |
| Melting point | 89-91 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol used for?
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This compound is primarily used as a chiral building block in organic synthesis, particularly in the preparation of complex carbohydrate derivatives and other enantiopure molecules for research and development in chemical biology and synthesis.
What are the CAS number and formula for this chemical?
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The CAS number is 51064-65-4, and the empirical formula is C21H26O8S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Refer to the safety data sheet for detailed handling and hazard information. The compound has a WGK Germany classification of 3.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol.
How can I request a sample or quote?
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Please contact our sales department or use the online inquiry form to request a sample or a detailed quotation for 1,4-Di-O-tosyl-2,3-O-isopropylidene-D-threitol.
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