1,4-Benzodioxan-6-sulfonyl chloride
1,4-Benzodioxan-6-sulfonyl chloride (CAS: 63758-12-3), with the empirical formula C8H7ClO4S and a molecular weight of 234.66 g/mol, is a key organic building block and a sulfonyl halide. It is primarily utilised in chemical synthesis, particularly for the construction of heterocyclic compounds. Its reactivity makes it a valuable intermediate in the development of novel molecules across various research and industrial applications.
- IUPAC
- 2,3-Dihydro-1,4-benzodioxine-6-sulfonyl chloride
- Synonyms
- 2,3-Dihydro-1,4-benzodioxine-6-sulfonyl chloride

Organic Synthesis Intermediate
This sulfonyl chloride serves as a crucial intermediate in organic synthesis. It is employed to introduce the 1,4-benzodioxan-6-sulfonyl moiety into other molecules, facilitating the creation of complex structures.
Heterocyclic Compound Synthesis
As a heterocyclic building block, it is instrumental in the synthesis of various heterocyclic frameworks. These structures are often found in pharmaceuticals and advanced materials.
Pharmaceutical Research
Its utility extends to pharmaceutical research and development, where it can be used in the synthesis of potential drug candidates or as a reagent in medicinal chemistry studies.
| Molecular weight | 234.66 |
|---|---|
| Empirical formula | C8H7ClO4S |
| Assay | 95% |
| Melting point | 65-70 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Benzodioxan-6-sulfonyl chloride used for?
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1,4-Benzodioxan-6-sulfonyl chloride is primarily used as a building block in organic synthesis and for the construction of heterocyclic compounds. It is also valuable in pharmaceutical research.
What are the CAS number and formula for 1,4-Benzodioxan-6-sulfonyl chloride?
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The CAS number is 63758-12-3, and the empirical formula is C8H7ClO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Benzodioxan-6-sulfonyl chloride with a minimum assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling this chemical?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). It reacts violently with water, necessitating careful handling and storage away from moisture.
How is 1,4-Benzodioxan-6-sulfonyl chloride packed and shipped?
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This product is packed and shipped according to international regulations for hazardous materials, including UN 3261, Class 8, Packing Group II. We export globally.
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the website or by phone, referencing the product name and CAS number (63758-12-3).
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