4-Bromobutyryl chloride
4-Bromobutyryl chloride (CAS 927-58-2) is a chemical intermediate with the linear formula BrCH2CH2CH2COCl and a molecular weight of 185.45 g/mol. This acid halide functions as a versatile building block in organic synthesis. It is primarily employed in the creation of more complex molecules within the pharmaceutical and chemical research sectors, serving as a key reagent in various synthetic pathways.

Pharmaceutical Intermediate
4-Bromobutyryl chloride serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its bifunctional nature allows for the introduction of specific chemical moieties during multi-step syntheses.
Organic Synthesis Reagent
This compound is utilised in general organic synthesis as an acylating agent. It enables the introduction of the 4-bromobutyryl group onto various nucleophiles, facilitating the construction of diverse organic structures.
Linker Molecule in Chemical Biology
The molecule can be employed as a linker in chemical biology research. Its ability to react with different functional groups on biomolecules allows for conjugation and the study of biological processes.
Research and Development
Primarily used in laboratory settings for R&D purposes, 4-Bromobutyryl chloride aids in exploring novel synthetic routes and developing new chemical entities across various scientific disciplines.
| Molecular weight | 185.45 |
|---|---|
| Linear formula | BrCH2CH2CH2COCl |
| Assay | ≥98.0% (GC) |
| Grade | purum |
| Boiling point | 101 °C/37 mmHg(lit.) |
| Density | 1.60 g/mL at 20 °C1.602 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.492(lit.)n20/D 1.493 |
| Storage temperature | 2-8°C |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34-37 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromobutyryl chloride primarily used for?
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4-Bromobutyryl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the pharmaceutical industry and chemical research for creating more complex molecules.
What are the CAS number and chemical formula for 4-Bromobutyryl chloride?
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The CAS number is 927-58-2, and its linear chemical formula is BrCH2CH2CH2COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromobutyryl chloride with a purity of ≥98.0% (GC) and a 'purum' grade. This product is intended for laboratory and research use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should 4-Bromobutyryl chloride be handled safely?
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4-Bromobutyryl chloride is a corrosive substance that reacts violently with water. It can cause severe skin burns and eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area, and keep away from moisture.
How is 4-Bromobutyryl chloride packed, shipped, and exported?
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Tech Serve Solutions ensures that 4-Bromobutyryl chloride is packed securely in compliance with transport regulations for hazardous materials. As a global supplier, we professionally export chemicals worldwide, adhering to all international shipping standards.
How can I request a quote or sample of 4-Bromobutyryl chloride?
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To request a quote or a sample of 4-Bromobutyryl chloride, please contact our sales department through the website or by phone. Our team will be pleased to assist you with your specific requirements.
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