1,4,8,11-Tetraazacyclotetradecane
1,4,8,11-Tetraazacyclotetradecane (CAS: 295-37-4; C10H24N4) is a macrocyclic amine with a molecular weight of 200.32 g/mol. Known commonly as Cyclam, this compound serves as a versatile ligand in coordination chemistry and is a key reagent in advanced polymer synthesis, particularly in Atom Transfer Radical Polymerization (ATRP). Its chelating properties make it valuable for forming stable complexes with various metal ions, finding utility in catalysis and materials science.
- IUPAC
- Cyclam
- Synonyms
- 11-TetraazacyclotetradecaneCyclam
Ligand in Coordination Chemistry
1,4,8,11-Tetraazacyclotetradecane acts as a tetradentate ligand, forming stable complexes with transition metal ions. These complexes are utilized in catalysis, mimicking enzyme active sites and in the development of new metallo-supramolecular architectures.
Atom Transfer Radical Polymerization (ATRP)
As an ATRP ligand, Cyclam is crucial for controlling the polymerization process, enabling the synthesis of polymers with well-defined architectures, molecular weights, and low polydispersity. This is vital for advanced materials development.
Chelation and Complexation
The compound's cyclic structure allows it to effectively chelate metal ions. This property is exploited in various chemical synthesis applications and for the sequestration or study of metal complexes.
Materials Science Research
It is employed in the synthesis of novel materials and coordination polymers. The ability to form stable metal complexes contributes to its use in developing functional materials with specific electronic or magnetic properties.
| Molecular weight | 200.32 |
|---|---|
| Empirical formula | C10H24N4 |
| Assay | 98% (GC) |
| Melting point | 184-186 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4,8,11-Tetraazacyclotetradecane used for?
+
This compound, commonly known as Cyclam, is primarily used as a ligand in coordination chemistry and as a key reagent in Atom Transfer Radical Polymerization (ATRP) for synthesizing polymers with controlled architectures. It is also used in chelation, complexation, and materials science research.
What are the CAS number and formula for 1,4,8,11-Tetraazacyclotetradecane?
+
The CAS number is 295-37-4, and its empirical formula is C10H24N4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1,4,8,11-Tetraazacyclotetradecane with a purity of 98% (GC). We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 1,4,8,11-Tetraazacyclotetradecane be handled?
+
Based on the supplied safety data, this compound can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves. Ensure good ventilation.
Is 1,4,8,11-Tetraazacyclotetradecane a controlled substance?
+
The provided data does not indicate that 1,4,8,11-Tetraazacyclotetradecane is a controlled substance.
How is 1,4,8,11-Tetraazacyclotetradecane packed and shipped?
+
Tech Serve Solutions exports fine chemicals globally. Specific packaging details are available upon request, and shipments comply with all relevant international regulations for chemical transport.
How can I request a quote or sample?
+
To request a quote or sample of 1,4,8,11-Tetraazacyclotetradecane, please contact our sales team through the website or call our dedicated support line.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis