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1,3-Propanediol

CAS 504-63-2HO(CH2)3OHChemical Synthesis

1,3-Propanediol (CAS 504-63-2), also known as Trimethylene glycol, is a colorless, viscous liquid with the molecular formula C3H8O2 and a molar mass of 76.09 g/mol. This diol serves as a versatile building block in organic synthesis and finds application as a solvent. Its chemical structure facilitates its use in polymerization reactions and as a synthon for various chemical transformations.

IUPAC
1,3-Dihydroxypropane,Bio-PDO,PG,Trimethylene glycol
Synonyms
HO(CH2)3OH1,3-DihydroxypropaneBio-PDOPGTrimethylene glycol
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1,3-Propanediol (HO(CH2)3OH) — chemical structure, CAS 504-63-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksOxygen CompoundsPolyols
01 /Applications

Solvent for Thin Film Preparations

1,3-Propanediol is employed as a solvent in the preparation of thin films. Its properties allow for the even distribution of materials during deposition processes.

Epoxide Chemistry

This compound functions as a vinyl epoxide synthon and is a key reagent for epoxide ring-opening reactions. It facilitates the introduction of the propanediol unit into various molecular structures.

Polymerization Reagent

1,3-Propanediol is utilised in polymerisation reactions. Its difunctional nature allows it to act as a monomer or chain extender in the synthesis of polymers.

Organic Synthesis Building Block

As a valuable organic building block, it is used in the synthesis of natural products and other complex organic molecules. It offers a three-carbon diol unit for synthetic strategies.

02 /Properties
Molecular weight76.09
Linear formulaHO(CH2)3OH
Assay98%
Boiling point214 °C/760 mmHg(lit.)
Density1.053 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.440(lit.)
SolubilityH2O: soluble
Melting point−27 °C(lit.)
Vapour pressure0.8 mmHg (20 °C)9.8 mmHg (100 °C)
Viscosity52 cP(20 °C)(lit.)
Impurities tested<0.1% water
ApplicationSolvent for thin film preparations.1 Vinyl epoxide synthon2 and reagent for epoxide ring-opening3 and polymerization reactions.4 Reagent for natural product syntheses.5
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
Protective equipmentEyeshields, Gloves
Flash point>110 °C / >230 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)38
Anion traceschloride (Cl-): <0.5 ppm

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
504-63-2
MDL number
MFCD00002949
PubChem substance
24898583
Beilstein registry
969155
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1,3-Propanediol used for?

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1,3-Propanediol is used as a solvent for thin film preparations, a vinyl epoxide synthon, a reagent for epoxide ring-opening and polymerisation reactions, and as a building block in natural product syntheses.

What is the CAS number and formula for 1,3-Propanediol?

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The CAS number for 1,3-Propanediol is 504-63-2 and its linear formula is HO(CH2)3OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1,3-Propanediol with an assay of 98%. We do not represent this product as USP, EP, BP, or any pharmacopoeia grade.

What are the safety considerations for handling 1,3-Propanediol?

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1,3-Propanediol is classified as a GHS07 irritant, with the signal word 'Warning' and hazard statement H315 (Causes skin irritation). Recommended personal protective equipment includes eyeshields and gloves. Handle in a well-ventilated area.

How is 1,3-Propanediol typically packed and shipped?

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1,3-Propanediol is available for global export from Tech Serve Solutions. Specific packing and shipping details are provided upon request and in accordance with international regulations.

How can I request a quote or sample of 1,3-Propanediol?

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To request a quote or sample of 1,3-Propanediol, please contact our sales team through the website or by phone. Please specify the quantity and destination for accurate quotation.

Need 1,3-Propanediol in a specific grade or volume?