1,3-Difluorobenzene
1,3-Difluorobenzene (CAS: 372-18-9), a fluorinated aromatic compound with the molecular formula C6H4F2 and a molecular weight of 114.09 g/mol, serves as a crucial building block in organic synthesis. This chemical, characterised by its two fluorine atoms positioned at the 1 and 3 positions on the benzene ring, is primarily employed in the development of pharmaceuticals, agrochemicals, and advanced materials where precise fluorination is required.
- Synonyms
- 1,3-Difluorobenzenem-Difluorobenzene
Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programmes. Its difluorinated structure can impart specific electronic and metabolic properties to drug molecules.
Agrochemical Synthesis
Serves as a precursor in the creation of novel pesticides and herbicides. The incorporation of fluorine atoms can enhance the efficacy and stability of agrochemical compounds.
Materials Science
Employed in the development of specialty polymers and liquid crystals. The unique properties conferred by the fluorine substituents are valuable in advanced material applications.
Organic Synthesis Reagent
A versatile building block for introducing the 1,3-difluorophenyl moiety into complex organic molecules. It is valuable in research and development settings for creating novel chemical entities.
| Molecular weight | 114.09 |
|---|---|
| Empirical formula | C6H4F2 |
| Assay | ≥99% |
| Boiling point | 82 °C(lit.) |
| Density | 1.163 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.438(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H332Harmful if inhaled
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 2 °C / 35.6 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-20 |
| Safety statements (S) | 7-16-29-33 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Difluorobenzene primarily used for?
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1,3-Difluorobenzene (CAS: 372-18-9) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials. Its difluorinated aromatic structure is valuable for introducing specific properties into target molecules.
What are the CAS number and molecular formula for 1,3-Difluorobenzene?
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The CAS number for 1,3-Difluorobenzene is 372-18-9, and its molecular formula is C6H4F2.
What grade and purity does Tech Serve Solutions supply for 1,3-Difluorobenzene?
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Tech Serve Solutions supplies 1,3-Difluorobenzene with an assay of ≥99%. This product is typically supplied as a research or technical grade, and TSS does not represent it as USP, BP, or EP grade.
How should 1,3-Difluorobenzene be handled safely?
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1,3-Difluorobenzene is a flammable liquid and vapour (H225) and harmful if inhaled (H332). Handling requires appropriate personal protective equipment, including eyeshields, face shield, gloves, and respiratory protection such as a full-face respirator or an ABEK-type filter. Ensure good ventilation and keep away from ignition sources. Consult the Safety Data Sheet for comprehensive handling instructions.
Is 1,3-Difluorobenzene a controlled substance?
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Based on the provided data, 1,3-Difluorobenzene (CAS: 372-18-9) is not indicated as a controlled substance.
How is 1,3-Difluorobenzene packed and exported by Tech Serve Solutions?
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1,3-Difluorobenzene is packed in accordance with safety regulations, typically in robust containers suitable for flammable liquids, and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 1,3-Difluorobenzene?
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To request a sample or a quote for 1,3-Difluorobenzene (CAS: 372-18-9), please contact the Tech Serve Solutions sales team via our website or direct contact details.
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