1,3-Difluoroacetone
1,3-Difluoroacetone (CAS 453-14-5) is a fluorinated ketone, a versatile organic building block. With a molar mass of 94.06 g/mol, this compound serves as a valuable intermediate in chemical synthesis. Its structure, featuring two fluorine atoms adjacent to a carbonyl group, imparts unique reactivity, making it useful in the development of novel organic molecules and materials. Offered by Tech Serve Solutions with an assay of 97%, it is suitable for research and development applications.
- IUPAC
- 1,3-Difluoro-2-propanone
- Synonyms
- 1,3-Difluoro-2-propanone

Organic Synthesis Intermediate
1,3-Difluoroacetone acts as a key building block in the synthesis of complex organic molecules. Its difluorinated structure can be incorporated into pharmaceuticals, agrochemicals, and advanced materials.
Fluorine Chemistry Research
This compound is utilised in academic and industrial research settings to explore new fluorination methodologies and to synthesise novel fluorinated compounds with potentially unique properties.
Precursor for Specialty Chemicals
It can serve as a precursor for the development of specialised fluorinated reagents and functional materials. The presence of fluorine atoms can significantly alter the physical and chemical characteristics of the final products.
| Assay | 97% |
|---|---|
| Density | 1.307 g/mL at 25 °C |
| Refractive index | n20/D 1.371 |
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Difluoroacetone used for?
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1,3-Difluoroacetone is used as a versatile intermediate in organic synthesis and in research for developing novel fluorinated compounds and materials.
What is the CAS number and formula for 1,3-Difluoroacetone?
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The CAS number is 453-14-5, and its molecular formula is C3H4F2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Difluoroacetone with a purity of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, EP, or BP grade.
How should 1,3-Difluoroacetone be handled?
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Handle 1,3-Difluoroacetone with appropriate personal protective equipment, including gloves and eye protection. Ensure adequate ventilation is present, as indicated by precautionary statements P261 and P280. In case of ingestion, seek immediate medical attention (P301 + P310, P311).
How is 1,3-Difluoroacetone shipped?
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1,3-Difluoroacetone is carefully packaged and exported by Tech Serve Solutions in compliance with all relevant shipping regulations for chemical substances.
How can I request a quote or sample of 1,3-Difluoroacetone?
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To request a quote or sample of 1,3-Difluoroacetone, please contact our sales team through the website or by phone, providing your specific requirements.
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