1,3-Dichloro-2-propanone
1,3-Dichloro-2-propanone (CAS: 534-07-6), also known as 1,3-dichloroacetone, is a key organic building block with the molecular formula C3H4Cl2O and a molecular weight of 126.97 g/mol. This compound functions as a versatile intermediate in chemical synthesis, particularly within the realms of organic chemistry and the development of pharmaceutical agents. Its reactive nature makes it valuable for introducing specific structural motifs in complex molecule construction.
- IUPAC
- 1,3-Dichloroacetone (sym.)
- Synonyms
- 1,3-Dichloroacetonesym-Dichloroacetone2,6-Dichloro-4-oxanonane
Organic Synthesis Intermediate
1,3-Dichloro-2-propanone serves as a crucial intermediate in various organic synthesis pathways. Its difunctional nature allows for participation in alkylation and cyclization reactions, enabling the construction of diverse heterocyclic compounds and complex organic structures.
Pharmaceutical Precursor
This compound is utilised in the synthesis of active pharmaceutical ingredients (APIs) and related intermediates. Its structure is amenable to transformations leading to valuable drug scaffolds, contributing to the development of new therapeutic agents.
Research and Development
In research laboratories, 1,3-dichloro-2-propanone is employed for exploring novel chemical reactions and developing new synthetic methodologies. Its predictable reactivity makes it a reliable reagent for academic and industrial R&D projects.
| Molecular weight | 126.97 |
|---|---|
| Linear formula | ClCH2COCH2Cl |
| Assay | ≥95.0% (GC) |
| Grade | purum |
| Boiling point | 173 °C(lit.) |
| Density | 1.383 g/mL at 25 °C(lit.) |
| Solubility | alcohol: very solublediethyl ether: very solublewater: soluble |
| Melting point | 38-43 °C |
| Vapour pressure | <0.1 mmHg (20 °C) |
| Vapour density | 4.38 (vs air) |
| Storage temperature | 2-8°C |
Hazard statements
- H300Fatal if swallowed
- H314Causes severe skin burns and eye damage
- H341Suspected of causing genetic defects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 89 °C / 192.2 °F |
| Transport (UN / ADR) | UN 2649 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 24-26/28-34-68 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Dichloro-2-propanone used for?
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1,3-Dichloro-2-propanone is primarily used as an intermediate in organic synthesis, particularly for the preparation of pharmaceutical agents and in chemical research and development.
What is the CAS number and chemical formula for 1,3-Dichloro-2-propanone?
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The CAS number is 534-07-6 and the linear formula is ClCH₂COCH₂Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Dichloro-2-propanone with a minimum assay of ≥95.0% (GC), designated as purum grade. TSS does not represent this product as USP, BP, or EP grade.
How should 1,3-Dichloro-2-propanone be handled?
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Due to its hazardous nature (Danger: toxic if swallowed, in contact with skin or inhaled; causes severe skin burns and eye damage; suspected of causing genetic defects), strict safety protocols are essential. Use appropriate personal protective equipment including eyeshields, faceshields, gloves, and a suitable respirator. Handle in a well-ventilated area or fume hood.
Is 1,3-Dichloro-2-propanone suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and can export 1,3-Dichloro-2-propanone.
How can I request a sample or quote for 1,3-Dichloro-2-propanone?
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Please contact our sales team via the website or direct enquiry channels to request a sample or a formal quotation for 1,3-Dichloro-2-propanone.
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