3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester

CAS 287944-16-5C11H19BO3Chemical Synthesis

3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester (CAS: 287944-16-5) is a boronate ester with the molecular formula C11H19BO3. This organometallic reagent is primarily utilised as a building block in organic synthesis. It serves as a valuable intermediate in the construction of complex molecules, particularly within pharmaceutical research and development, owing to the versatility of boronic acid derivatives in cross-coupling reactions.

IUPAC: 2-(3,6-Dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms: 2-(3,6-Dihydro-2H-pyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

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3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester (C11H19BO3) — chemical structure, CAS 287944-16-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Boronate EstersChemical SynthesisHeteroaryl Boronate EstersOrganometallic Reagents

01 /Applications

Organic Synthesis Intermediate

This compound functions as a key intermediate in organic synthesis, enabling the introduction of the 3,6-dihydro-2H-pyran-4-yl moiety into various molecular architectures.

Cross-Coupling Reactions

As a boronate ester, it is well-suited for participation in transition-metal catalysed cross-coupling reactions, such as Suzuki-Miyaura couplings, facilitating the formation of carbon-carbon bonds.

Pharmaceutical Research

It serves as a valuable building block for medicinal chemists engaged in the discovery and development of novel pharmaceutical agents, aiding in the synthesis of complex drug candidates.

Heterocyclic Chemistry

The molecule's structure makes it useful in the synthesis of various heterocyclic compounds, which are prevalent in biologically active molecules.

02 /Properties

Molecular weight	210.08
Empirical formula	C11H19BO3
Assay	97%
Storage temperature	2-8°C
Melting point	63-67 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

287944-16-5

MDL number

MFCD11052631

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester used for?

This compound is primarily used as an intermediate in organic synthesis and for participation in cross-coupling reactions, particularly within pharmaceutical research for constructing complex molecules and heterocyclic compounds.

What is the CAS number and formula for 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester?

The CAS number is 287944-16-5 and the empirical formula is C11H19BO3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester with an assay of 97%. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling considerations for this compound?

This compound is classified with GHS07 symbol and a 'Warning' signal word, carrying the hazard statement H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area. Storage at 2-8°C is recommended.

How is this product packed, shipped, and exported?

Tech Serve Solutions offers robust packaging suitable for fine chemicals, ensuring safe transport and export globally. Specific packaging details can be provided upon request.

How can I request a sample or quote for 3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester?

To request a sample or a quotation, please contact our sales department via the website or direct email, specifying the product CAS number 287944-16-5.