3,6-Difluoropyridine-2-carboxylic acid

CAS 851386-45-3C6H3F2NO2Chemical Synthesis

3,6-Difluoropyridine-2-carboxylic acid (CAS: 851386-45-3) is a fluorinated heterocyclic compound with the molecular formula C6H3F2NO2. This building block is primarily used in chemical synthesis, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring a pyridine ring substituted with two fluorine atoms and a carboxylic acid group, makes it a valuable intermediate for creating complex organic molecules and novel active pharmaceutical ingredients (APIs).

Synonyms: C6H3F2NO2

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3,6-Difluoropyridine-2-carboxylic acid (C6H3F2NO2) — chemical structure, CAS 851386-45-3; Chemistry, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Pharmaceutical Intermediate

Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs). Its fluorinated pyridine structure can impart desirable pharmacokinetic properties.

Agrochemical Synthesis

Utilised in the development of new pesticides, herbicides, and fungicides. The incorporation of fluorine atoms can enhance the efficacy and metabolic stability of agrochemical compounds.

Organic Synthesis Reagent

Acts as a versatile synthon in organic chemistry for introducing a difluoropyridine moiety into various molecular structures. Useful in medicinal chemistry research and development.

Material Science Research

Potentially employed in the synthesis of functional materials where fluorinated heterocyclic motifs are required for specific electronic or physical properties.

02 /Properties

Molecular weight	159.09
Empirical formula	C6H3F2NO2
Assay	97%
Storage temperature	2-8°C
Melting point	147-152 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

851386-45-3

MDL number

MFCD09031176

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3,6-Difluoropyridine-2-carboxylic acid used for?

3,6-Difluoropyridine-2-carboxylic acid is primarily used as a building block in chemical synthesis, particularly for pharmaceutical and agrochemical research and development, enabling the creation of complex fluorinated heterocyclic compounds.

What are the CAS number and molecular formula for 3,6-Difluoropyridine-2-carboxylic acid?

The CAS number is 851386-45-3 and the molecular formula is C6H3F2NO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3,6-Difluoropyridine-2-carboxylic acid with a purity of 97%. This product is suitable for chemical synthesis and research purposes. TSS does not represent this product as USP, BP, or EP grade.

How should 3,6-Difluoropyridine-2-carboxylic acid be handled and stored?

This compound is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, wear protective gloves and eye protection. Store at 2-8°C.