1-(3-Aminophenyl)pyrrolidin-2-one
1-(3-Aminophenyl)pyrrolidin-2-one (CAS 31992-43-5) is an organic building block with the molecular formula C10H12N2O and a molar mass of 176.22 g/mol. It pairs a primary aromatic amine on a benzene ring with an N-aryl pyrrolidin-2-one (a five-membered gamma-lactam), giving two complementary reactive handles. Tech Serve Solutions supplies it as a research-grade heterocyclic intermediate for chemical synthesis, medicinal-chemistry exploration and pyrrolidinone-based scaffold development.
- Synonyms
- 1-(3-Aminophenyl)pyrrolidin-2-one1-(3-aminophenyl)-2-pyrrolidinone1-(3-aminophenyl)pyrrolidin-2-one3-(2-oxopyrrolidin-1-yl)anilineCAS 31992-43-5

Heterocyclic building block
Used as a pyrrolidinone-containing scaffold in chemical synthesis, where the preformed N-aryl gamma-lactam ring is carried directly into more elaborate target molecules.
Aromatic amine for derivatisation
The free 3-amino group is a versatile handle for acylation, sulfonylation, reductive amination, diazotisation and amide or urea formation, enabling rapid analogue generation.
Medicinal-chemistry intermediate
Serves as an intermediate and starting material in early-stage medicinal-chemistry and discovery programmes that require an aniline tethered to a 2-pyrrolidinone ring.
Cross-coupling and amide-bond chemistry
The aromatic amine supports palladium-catalysed C-N coupling and condensation routes, allowing the compound to be incorporated as a coupling partner within larger conjugates.
Reference and research use
Suitable as a defined-structure intermediate for laboratory research and method development where a single, well-characterised C10H12N2O building block is needed.
| Molecular weight | 176.22 |
|---|---|
| Empirical formula | C10H12N2O |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(3-Aminophenyl)pyrrolidin-2-one used for?
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It is used primarily as a building block and intermediate in chemical synthesis. The combination of a primary aromatic amine and an N-aryl pyrrolidin-2-one (gamma-lactam) ring makes it useful for derivatisation, amide and urea formation, and the construction of pyrrolidinone-based scaffolds in medicinal-chemistry and discovery research.
What is the CAS number and molecular formula of 1-(3-Aminophenyl)pyrrolidin-2-one?
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Its CAS number is 31992-43-5 and its molecular formula is C10H12N2O, with a molecular weight of 176.22 g/mol (Hill notation C10H12N2O).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade synthesis intermediate. We do not represent it as USP, BP or EP pharmacopoeial grade. A current specification and Certificate of Analysis, including the batch assay, are provided with each order on request.
How should 1-(3-Aminophenyl)pyrrolidin-2-one be handled and stored?
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Handle it as a laboratory chemical using good practice: wear suitable gloves, eye protection and a lab coat, work with adequate ventilation, and avoid dust, skin and eye contact. As an aromatic amine, contact and inhalation should be minimised. Store in a tightly closed container in a cool, dry, well-ventilated place away from strong oxidisers. No GHS classification data is supplied with this record; always refer to the accompanying Safety Data Sheet before use.
How is 1-(3-Aminophenyl)pyrrolidin-2-one packed, shipped and exported?
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It is packed in sealed, appropriately labelled containers sized from research quantities upward, with packaging selected to protect the material in transit. As a specialist exporter, Tech Serve Solutions ships worldwide with full documentation, including the Certificate of Analysis and Safety Data Sheet, and arranges transport in line with applicable regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 31992-43-5. We will respond with availability, specification, lead time and a formal quotation, and can arrange a sample where appropriate.
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