1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt
1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt (CAS: 953758-30-0), with the empirical formula C34H70NO10P, is a synthetic glycerophospholipid. This compound is a key component in the development of liposome formulations for drug delivery. It has been extensively studied for its role in encapsulating various therapeutic agents, including platinum-based anticancer drugs and antifungal compounds, contributing to advancements in pharmaceutical research and development.
- IUPAC
- 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol ammonium salt,1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) ammonium salt,L-α-Phosphatidyl-DL-glycerol, dimyristoyl ammonium salt,DMPG-NH4,PG(14:0/14:0),Tetradecanoic acid 1,1′-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester monoammonium salt
- Synonyms
- 1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol ammonium salt1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) ammonium saltL-α-Phosphatidyl-DL-glycerol, dimyristoyl ammonium saltDMPG-NH4PG(14:0/14:0)Tetradecanoic acid 1,1′-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester monoammonium salt
Liposome Encapsulation
Utilised as a neutral lipid in the formulation of highly defined mixed-lipid liposomes. This application is crucial for encapsulating drugs like platinum complexes, enhancing their targeted delivery and efficacy in cancer therapy.
Antifungal Vaccine Research
Investigated for its potential use in developing anti-Candida vaccines. It has been employed in studies involving Candida albicans ribosomes, exploring novel strategies for combating fungal infections.
Drug Delivery Systems
Serves as a vital component in creating advanced drug delivery systems. Its incorporation into liposomes allows for the controlled release and improved bioavailability of various therapeutic agents, including antifungal agents like hamycin.
| Empirical formula | C34H70NO10P |
|---|---|
| Assay | ≥97.0% (TLC) |
| Storage temperature | −20°C |
| Application | Has been used as the neutral lipid in studies of highly defined mixed-lipid liposome encapsulated drugs, e.g., a platinum complex antitumor agent,1 the antifungal agent hamycin,2 and Candida albicans ribosomes as an anti-Candida vaccine.3 |
| Biological source | from synthetic |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt used for?
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This compound is used in the formulation of liposomes for drug delivery, including anticancer agents and antifungal compounds, and in research for anti-Candida vaccines.
What is the CAS number and empirical formula for this product?
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The CAS number is 953758-30-0 and the empirical formula is C34H70NO10P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a purity of ≥97.0% (TLC). It is supplied for research and development purposes and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How is this chemical handled and what are the safety considerations?
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Handling requires appropriate personal protective equipment including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The product carries a WGK of 3 in Germany, indicating a high hazard to water.
How is 1,2-Dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) ammonium salt packed and shipped?
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This chemical is typically stored at -20°C and is carefully packaged and exported by TSS to maintain its integrity during transit.
How can I request a sample or quote for this product?
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You can request a sample or obtain a quote by contacting our sales team via the website or direct inquiry.
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