1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt
1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt (CAS: 321595-13-5) is a synthetic phospholipid with a molecular weight of 814.06 g/mol. It is a key component in cell biology research, particularly in studies of glycerophospholipid metabolism and metabolomics. This compound serves as a valuable tool for investigating phase transitions in lipid bilayers and cholesterol-phospholipid mixtures, contributing to a deeper understanding of membrane structure and function.
- IUPAC
- (2S,8R)-2-Amino-5-hydroxy-11-oxo-8-[(1-oxooctadecyl)oxy]-4,6,10-trioxa-5-phosphaoctacosanoic acid 5-oxide sodium salt,1,2-Dioctadecanoyl-sn-glycero-3-phospho-L-serine sodium salt,1,2-Dioctadecanoyl-sn-glycero-3-phosphoserine sodium salt,3-sn-Phosphatidyl-L-serine, distearoyl sodium salt,DSPS-Na,PS(18:0/18:0)
- Synonyms
- C42H81NNaO10P(2S,8R)-2-Amino-5-hydroxy-11-oxo-8-[(1-oxooctadecyl)oxy]-4,6,10-trioxa-5-phosphaoctacosanoic acid 5-oxide sodium salt1,2-Dioctadecanoyl-sn-glycero-3-phospho-L-serine sodium salt1,2-Dioctadecanoyl-sn-glycero-3-phosphoserine sodium salt3-sn-Phosphatidyl-L-serine, distearoyl sodium saltDSPS-NaPS(18:0/18:0)
Lipid Bilayer Research
Investigate the physical properties of cell membranes, including phase transitions and miscibility with other lipids like cholesterol. Its defined structure makes it ideal for creating model membranes.
Glycerophospholipid Metabolism Studies
Utilise as a substrate or component in research focused on the synthesis, degradation, and regulatory pathways of glycerophospholipids within biological systems.
Metabolomics and Metabolic Pathway Analysis
Employ in metabolomics studies to identify and quantify lipid metabolites, aiding in the elucidation of complex metabolic pathways and their roles in cellular function and disease.
Cholesterol-Phospholipid Interaction Studies
Examine the precise interactions and phase behaviour between phospholipids, such as DSPS-Na, and cholesterol in different lipid phases, providing insights into membrane fluidity and integrity.
| Molecular weight | 814.06 |
|---|---|
| Empirical formula | C42H81NNaO10P |
| Assay | ≥75% (TLC) |
| Storage temperature | −20°C |
| Application | In a study of phase transitions in cholesterol-phospholipid mixtures, cholesterol was found to be much less miscible with DSPS in the gel phase than the liquid crystal phase; up to 50 mol % cholesterol fails to abolish the hydrocarbon chain-melting phase transition.1 |
| Biological source | from synthetic |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt used for?
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This compound is primarily used in cell biology research, particularly for studying glycerophospholipid metabolism, metabolomics, and phase transitions in cholesterol-phospholipid mixtures.
What are the CAS number and formula for this product?
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The CAS number is 321595-13-5 and the empirical formula (Hill notation) is C42H81NNaO10P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥75% (TLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling requirements?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK Germany classification of 3, indicating a hazard to water.
How is this chemical packed and shipped?
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The chemical is typically stored at -20°C and shipped according to standard procedures for sensitive reagents. Please contact us for specific export and shipping details.
How can I request a sample or a quote?
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To request a sample or a quote for 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt, please visit our website or contact our sales department directly.
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