1,2-Dichloro-4-fluoro-5-nitrobenzene
1,2-Dichloro-4-fluoro-5-nitrobenzene (CAS: 2339-78-8) is an organic compound with the molecular formula Cl2C6H2(F)NO2 and a molecular weight of 209.99 g/mol. This fluorinated nitroaromatic compound serves as a valuable building block in organic synthesis. It is primarily utilised in the chemical industry for the development of more complex molecules and speciality chemicals, particularly where precise fluorination and substitution patterns are required.
- Synonyms
- Cl2C6H2(F)NO2

Chemical Synthesis Intermediate
1,2-Dichloro-4-fluoro-5-nitrobenzene is employed as an intermediate in the synthesis of various organic compounds. Its reactive halogen and nitro groups allow for diverse chemical transformations.
Fluorinated Building Block
This compound is a key component in the introduction of fluorinated aromatic moieties into larger molecular structures. It is valuable in the research and development of pharmaceuticals and agrochemicals.
Research and Development
Utilised in laboratory settings for the exploration of new chemical pathways and the creation of novel materials. Its specific substitution pattern makes it a useful reagent for targeted synthesis.
| Molecular weight | 209.99 |
|---|---|
| Linear formula | Cl2C6H2(F)NO2 |
| Assay | 95% |
| Boiling point | 247 °C(lit.) |
| Density | 1.596 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.575(lit.) |
| Melting point | 17 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2-Dichloro-4-fluoro-5-nitrobenzene used for?
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1,2-Dichloro-4-fluoro-5-nitrobenzene is primarily used as an intermediate in organic synthesis and as a fluorinated building block for the development of complex organic molecules and speciality chemicals.
What is the CAS number and formula for 1,2-Dichloro-4-fluoro-5-nitrobenzene?
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The CAS number is 2339-78-8, and its linear formula is Cl2C6H2(F)NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2-Dichloro-4-fluoro-5-nitrobenzene with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 1,2-Dichloro-4-fluoro-5-nitrobenzene be handled safely?
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1,2-Dichloro-4-fluoro-5-nitrobenzene is classified as harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. Appropriate personal protective equipment including eyeshields, face shields, gloves, and suitable respiratory protection must be used. Handle in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 1,2-Dichloro-4-fluoro-5-nitrobenzene available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,2-Dichloro-4-fluoro-5-nitrobenzene.
How can I request a sample or quote for 1,2-Dichloro-4-fluoro-5-nitrobenzene?
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Please contact our sales team via the website or directly via email to request a sample or a quotation for 1,2-Dichloro-4-fluoro-5-nitrobenzene.
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