1,2,4-Trimethoxybenzene
1,2,4-Trimethoxybenzene (CAS: 135-77-3) is an aromatic organic compound with the linear formula C6H3(OCH3)3 and a molecular weight of 168.19 g/mol. This ether, also known as hydroxyhydroquinone trimethyl ether, is supplied by TSS at 97% purity. It serves as a valuable building block in organic synthesis, particularly in the creation of more complex molecules within the pharmaceutical and chemical industries.
- IUPAC
- Hydroxyhydroquinone trimethyl ether
- Synonyms
- 135-77-3C6H3(OCH3)3Hydroxyhydroquinone trimethyl ether

Organic Synthesis Intermediate
1,2,4-Trimethoxybenzene is utilised as a key intermediate in multi-step organic syntheses. Its specific arrangement of methoxy groups on the benzene ring allows for targeted chemical transformations.
Research and Development
This compound is employed in laboratory settings for research purposes, enabling the exploration of new chemical pathways and the development of novel compounds.
Fine Chemical Manufacturing
As a C9 organic building block, it finds application in the manufacturing of fine chemicals, contributing to the production of specialised chemical products.
| Molecular weight | 168.19 |
|---|---|
| Linear formula | C6H3(OCH3)3 |
| Assay | 97% |
| Boiling point | 247 °C(lit.) |
| Density | 1.126 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.533(lit.) |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,4-Trimethoxybenzene primarily used for?
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1,2,4-Trimethoxybenzene is primarily used as an intermediate in organic synthesis and in research and development for creating novel chemical compounds.
What are the CAS number and formula for 1,2,4-Trimethoxybenzene?
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The CAS number is 135-77-3, and the linear formula is C6H3(OCH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,4-Trimethoxybenzene with an assay of 97%. This product is not supplied as USP, BP, or EP grade.
What are the safety and handling considerations for 1,2,4-Trimethoxybenzene?
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1,2,4-Trimethoxybenzene has a flash point of 113 °C (235.4 °F) and is classified with WGK Germany 3. Appropriate personal protective equipment, including eyeshields and gloves, should be used when handling this compound.
How is 1,2,4-Trimethoxybenzene packed, shipped, and exported?
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1,2,4-Trimethoxybenzene is carefully packed and exported by TSS according to international shipping regulations for chemicals.
How can I request a quote or sample for 1,2,4-Trimethoxybenzene?
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To request a quote or sample of 1,2,4-Trimethoxybenzene, please contact the TSS sales team via our website or direct inquiry.
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