1,2,4-Trifluorobenzene
1,2,4-Trifluorobenzene (CAS: 367-23-7) is a halogenated aromatic hydrocarbon with the molecular formula C6H3F3 and a molecular weight of 132.08 g/mol. This compound serves as a valuable fluorinated building block in organic synthesis. It is primarily employed in the research and development of pharmaceuticals, agrochemicals, and advanced materials due to its unique reactivity conferred by the fluorine substituents.
- Synonyms
- 367-23-7C6H3F3
Organic Synthesis Intermediate
1,2,4-Trifluorobenzene is a versatile intermediate for introducing fluorinated phenyl groups into complex organic molecules. Its specific substitution pattern allows for regioselective reactions in the synthesis of advanced materials and fine chemicals.
Pharmaceutical Research
This compound is utilised in the exploratory synthesis of novel pharmaceutical candidates. The incorporation of fluorine atoms can modify a drug molecule's metabolic stability, lipophilicity, and binding affinity.
Agrochemical Development
Fluorinated aromatic compounds like 1,2,4-Trifluorobenzene are investigated for their potential in developing new pesticides and herbicides. Fluorine substitution can enhance the biological activity and environmental persistence of agrochemicals.
Materials Science
It can be used as a precursor in the synthesis of functional materials, including polymers and liquid crystals, where the presence of fluorine imparts desirable thermal and electronic properties.
| Molecular weight | 132.08 |
|---|---|
| Empirical formula | C6H3F3 |
| Assay | 98% |
| Boiling point | 88 °C/759 mmHg(lit.) |
| Density | 1.264 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.423(lit.) |
Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 4 °C / 39.2 °F |
| Transport (UN / ADR) | UN 1993BE 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,4-Trifluorobenzene used for?
+
1,2,4-Trifluorobenzene is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials. It is valuable for introducing fluorinated aromatic moieties.
What is the CAS number and molecular formula for 1,2,4-Trifluorobenzene?
+
The CAS number for 1,2,4-Trifluorobenzene is 367-23-7, and its molecular formula is C6H3F3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1,2,4-Trifluorobenzene with a minimum assay of 98%. This product is suitable for research and chemical synthesis and is not represented as USP, BP, or EP grade.
How should 1,2,4-Trifluorobenzene be handled safely?
+
1,2,4-Trifluorobenzene is a flammable liquid and an irritant. Handle in a well-ventilated area, away from ignition sources. Wear appropriate personal protective equipment, including gloves, safety glasses, and a respirator if ventilation is inadequate. Refer to the Safety Data Sheet for comprehensive guidance.
How is 1,2,4-Trifluorobenzene packed and exported?
+
1,2,4-Trifluorobenzene is packed according to international shipping regulations for hazardous materials and is available for export worldwide by Tech Serve Solutions.
How can I request a quote or sample for 1,2,4-Trifluorobenzene?
+
To request a quote or sample of 1,2,4-Trifluorobenzene, please contact the Tech Serve Solutions sales team via our website or directly by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis