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L-Tyrosine tert-butyl ester

CAS 16874-12-7HOC6H4CH2CH(NH2)COOC(CH3)3Chemical Synthesis

L-Tyrosine tert-butyl ester (CAS: 16874-12-7) is a derivative of the amino acid L-Tyrosine, with its carboxyl group protected as a tert-butyl ester. This modification enhances its solubility in organic solvents and prevents unwanted reactions during synthesis. It is a valuable building block in peptide chemistry and organic synthesis, particularly for incorporating tyrosine residues into peptides and complex molecules.

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L-Tyrosine tert-butyl ester (HOC6H4CH2CH(NH2)COOC(CH3)3) — chemical structure, CAS 16874-12-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Amino Acid DerivativesChemical BiologyChemical SynthesisPeptide ChemistryTyrosine
01 /Applications

Peptide Synthesis

L-Tyrosine tert-butyl ester serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis, facilitating the construction of peptides containing tyrosine.

Organic Synthesis

The tert-butyl ester functionality allows for selective manipulation of the tyrosine side chain in multi-step organic synthesis projects, enabling the creation of complex chemical structures.

Chemical Biology Research

Used in research settings for developing modified peptides or small molecules with potential biological activity, leveraging the unique properties of the protected tyrosine moiety.

02 /Properties
Molecular weight237.29
Linear formulaHOC6H4CH2CH(NH2)COOC(CH3)3
Assay≥99.0% (NT)
Optical activity[α]20/D +25±1°, c = 2% in ethanol
Melting point141-144 °C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
16874-12-7
MDL number
MFCD00042644
Beilstein registry
2696011
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is L-Tyrosine tert-butyl ester used for?

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L-Tyrosine tert-butyl ester is primarily used as a protected amino acid in peptide synthesis and as a building block in organic synthesis for creating complex molecules.

What is the CAS number and formula for L-Tyrosine tert-butyl ester?

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The CAS number is 16874-12-7. The linear formula is HOC6H4CH2CH(NH2)COOC(CH3)3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies L-Tyrosine tert-butyl ester with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade unless explicitly stated in the product specifications.

What are the safety and handling precautions for L-Tyrosine tert-butyl ester?

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L-Tyrosine tert-butyl ester is classified under WGK Germany 3. Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. Avoid contact with skin and eyes, and ensure adequate ventilation.

How is L-Tyrosine tert-butyl ester packed, shipped, and exported?

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Tech Serve Solutions carefully packs and ships chemicals globally, adhering to all relevant transportation and export regulations for chemical compounds.

How can I request a sample or quote for L-Tyrosine tert-butyl ester?

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To request a sample or a detailed quotation, please contact our sales department through the website or by phone, referencing the product name and CAS number.

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