3-Aminooxetane
3-Aminooxetane (CAS 21635-88-1, C3H7NO, MW 73.09) is a vital heterocyclic building block used in chemical synthesis. This oxetane derivative is characterised by its unique four-membered ring structure, offering distinct reactivity for developing novel molecules. It serves as a key intermediate in the research and development of pharmaceuticals and advanced materials, valued for its potential to introduce the oxetane motif into complex organic structures.
- IUPAC
- 3-Oxetanamine

Pharmaceutical Intermediates
3-Aminooxetane is employed as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its oxetane ring can impart desirable physicochemical properties to drug candidates, influencing solubility, metabolic stability, and cell permeability.
Organic Synthesis
As a versatile reagent, it is utilised in various organic transformations to construct complex molecular architectures. The amine functionality and the strained oxetane ring allow for diverse derivatisation pathways.
Materials Science Research
The compound finds application in the development of novel materials, where the oxetane moiety can influence polymer properties or act as a functional handle for further modifications.
| Molecular weight | 73.09 |
|---|---|
| Empirical formula | C3H7NO |
| Assay | 97% |
| Density | 1.042 g/mL at 25 °C |
| Refractive index | n20/D 1.453 |
| Storage temperature | −20°C |



Hazard statements
- H226Flammable liquid and vapour
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Flash point | 24 °C / 75.2 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 10-22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Aminooxetane used for?
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3-Aminooxetane is primarily used as a building block in organic synthesis, particularly for developing pharmaceutical intermediates and novel materials. Its unique heterocyclic structure makes it valuable for introducing the oxetane motif into complex molecules.
What are the CAS number and formula for 3-Aminooxetane?
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The CAS number for 3-Aminooxetane is 21635-88-1, and its empirical formula is C3H7NO.
What grade and purity does Tech Serve Solutions supply for 3-Aminooxetane?
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Tech Serve Solutions supplies 3-Aminooxetane with an assay of 97%. This product is supplied for research and development purposes and is not intended for use as a USP, BP, EP, or pharmaceutical grade material.
How should 3-Aminooxetane be handled safely?
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3-Aminooxetane is a flammable liquid and vapour (H226) and is acutely toxic if swallowed (H301), causing serious eye damage (H318). Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment, including gloves, eye protection, and respiratory protection. Store away from ignition sources at -20°C.
How is 3-Aminooxetane packed and shipped?
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3-Aminooxetane is carefully packed in compliance with international shipping regulations for hazardous materials. It is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote for 3-Aminooxetane?
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To request a sample or a quote for 3-Aminooxetane, please contact our sales team through the website or by calling our main office. Please specify the quantity and your delivery location.
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