1,2,4,5-Tetrafluorobenzene
1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8; C6H2F4) is a halogenated aromatic compound with a molecular weight of 150.07 g/mol. Possessing a high degree of fluorination, it serves as a valuable building block in organic synthesis. Its specific structure lends itself to incorporation into more complex molecules, finding utility in the development of novel materials and chemical intermediates.
- Synonyms
- 1,2,4,5-Tetrafluorobenzene327-54-8C6H2F4

Organic Synthesis Intermediate
1,2,4,5-Tetrafluorobenzene is employed as a key intermediate in the synthesis of various organic compounds. Its reactive sites allow for further functionalisation, enabling the creation of complex fluorinated molecules.
Fluorinated Building Block
This compound acts as a crucial building block in the design and synthesis of advanced materials. Its fluorinated aromatic structure can impart unique electronic and physical properties to target molecules.
Research and Development
Utilised in academic and industrial research settings, 1,2,4,5-Tetrafluorobenzene aids in exploring new chemical pathways and developing novel fluorinated compounds for diverse applications.
| Molecular weight | 150.07 |
|---|---|
| Empirical formula | C6H2F4 |
| Assay | ≥99% |
| Boiling point | 90 °C(lit.) |
| Density | 1.344 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.407(lit.) |
| Melting point | 4 °C(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 16 °C / 60.8 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,4,5-Tetrafluorobenzene used for?
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1,2,4,5-Tetrafluorobenzene is primarily used as an intermediate in organic synthesis and as a building block for fluorinated compounds in research and development.
What are the CAS number and formula for 1,2,4,5-Tetrafluorobenzene?
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The CAS number is 327-54-8 and the empirical formula is C6H2F4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,4,5-Tetrafluorobenzene with a minimum assay of ≥99%. This product is suitable for research and general chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 1,2,4,5-Tetrafluorobenzene be handled safely?
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1,2,4,5-Tetrafluorobenzene is a flammable liquid and vapour (H225) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, wearing appropriate personal protective equipment including safety goggles, gloves, and a suitable respirator.
Is 1,2,4,5-Tetrafluorobenzene supplied internationally?
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Yes, Tech Serve Solutions exports and supplies 1,2,4,5-Tetrafluorobenzene globally.
How can I request a sample or quote for 1,2,4,5-Tetrafluorobenzene?
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To request a sample or obtain a quotation for 1,2,4,5-Tetrafluorobenzene, please contact our sales team via the website or direct inquiry.
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