1,2,4,5-Tetrabromobenzene
1,2,4,5-Tetrabromobenzene (CAS: 636-28-2, C6H2Br4) is a brominated aromatic compound with a molecular weight of 393.70 g/mol. This chemical is utilised as a building block in organic synthesis, particularly in the preparation of complex molecules. Its structure makes it valuable for introducing multiple bromine atoms onto an aromatic core, facilitating further chemical transformations in research and development settings.
- Synonyms
- 5-TetrabromobenzeneC6H2Br4

Synthesis of Ligands
1,2,4,5-Tetrabromobenzene has been employed in synthetic routes for creating specialised ligands, such as diethynyltriptycene-linked dipyridyl ligands, which are relevant in coordination chemistry and materials science research.
Organic Building Block
As a halogenated hydrocarbon, this compound serves as a versatile building block in organic synthesis. The multiple bromine substituents allow for various cross-coupling reactions and other derivatizations, contributing to the construction of novel organic structures.
Chemical Research and Development
The compound is utilised in academic and industrial laboratories for exploring new synthetic methodologies and developing novel materials. Its well-defined structure facilitates predictable reactions in multi-step syntheses.
| Molecular weight | 393.70 |
|---|---|
| Empirical formula | C6H2Br4 |
| Assay | 97% |
| Application | 1,2,4,5-Tetrabromobenzene has been used in the synthesis of diethynyltriptycene-linked dipyridyl ligands1. |
| Melting point | 180-182 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,2,4,5-Tetrabromobenzene used for?
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1,2,4,5-Tetrabromobenzene is used as a building block in organic synthesis, including the preparation of specialised ligands and in general chemical research and development.
What is the CAS number and formula for 1,2,4,5-Tetrabromobenzene?
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The CAS number for 1,2,4,5-Tetrabromobenzene is 636-28-2 and its empirical formula is C6H2Br4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,2,4,5-Tetrabromobenzene with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1,2,4,5-Tetrabromobenzene be handled safely?
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Handle 1,2,4,5-Tetrabromobenzene with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation to avoid inhalation of dust. This compound is a skin, eye, and respiratory irritant.
Is 1,2,4,5-Tetrabromobenzene shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1,2,4,5-Tetrabromobenzene.
How can I request a quote or sample?
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Please contact our sales team directly via the website or by phone to request a quote or to arrange for a sample of 1,2,4,5-Tetrabromobenzene.
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