1-[2-(2-Hydroxyethoxy)ethyl]piperazine
1-[2-(2-Hydroxyethoxy)ethyl]piperazine (CAS: 13349-82-1), with the molecular formula C8H18N2O2 and a molecular weight of 174.24 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its structure, featuring a piperazine ring with an ethoxyethanol substituent, makes it suitable for various derivatisation reactions.
- IUPAC
- 2-[2-(1-Piperazinyl)ethoxy]ethanol
![1-[2-(2-Hydroxyethoxy)ethyl]piperazine (C8H18N2O2) — chemical structure, CAS 13349-82-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F13349-82-1.png&w=3840&q=75)
Chemical Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of more complex organic molecules. Its reactive sites allow for diverse chemical modifications, making it useful in multi-step synthetic pathways.
Heterocyclic Building Block
As a substituted piperazine, it is employed in the construction of novel heterocyclic compounds. These structures are often foundational in the development of pharmaceuticals and advanced materials.
Research and Development
Utilised in academic and industrial research settings for exploring new chemical entities and reaction methodologies. Its specific structural features lend themselves to investigations in medicinal chemistry and material science.
| Molecular weight | 174.24 |
|---|---|
| Empirical formula | C8H18N2O2 |
| Assay | 95% |
| Boiling point | 112-114 °C/0.25 mmHg(lit.) |
| Density | 1.061 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.497(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-[2-(2-Hydroxyethoxy)ethyl]piperazine used for?
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1-[2-(2-Hydroxyethoxy)ethyl]piperazine (CAS: 13349-82-1) is primarily used as a building block in chemical synthesis and for research and development purposes, particularly in the field of heterocyclic chemistry.
What is the CAS number and formula for this compound?
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The CAS number for 1-[2-(2-Hydroxyethoxy)ethyl]piperazine is 13349-82-1, and its empirical formula is C8H18N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-[2-(2-Hydroxyethoxy)ethyl]piperazine with an assay of 95%. This is considered a technical or research grade; TSS does not represent it as USP, BP, or EP grade.
How should 1-[2-(2-Hydroxyethoxy)ethyl]piperazine be handled safely?
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This compound is classified with GHS07 warning, indicating it can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used during handling. It is flammable with a flash point of 113 °C (235.4 °F).
Is 1-[2-(2-Hydroxyethoxy)ethyl]piperazine a controlled substance?
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The provided data does not indicate that 1-[2-(2-Hydroxyethoxy)ethyl]piperazine is a controlled substance.
How is this chemical packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Packaging is handled according to stringent safety and regulatory standards to ensure product integrity and compliance during international transit.
How can I request a sample or a quote?
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To request a sample or a quotation for 1-[2-(2-Hydroxyethoxy)ethyl]piperazine, please contact the TSS sales department through the website or direct contact information provided.
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