1,1,3,3-Tetramethoxypropane
1,1,3,3-Tetramethoxypropane (CAS: 102-52-3), with the molecular formula C7H16O4 and a molecular weight of 164.20 g/mol, is a versatile organic compound. Also known as malonaldehyde bis(dimethyl acetal), it serves as a key intermediate and building block in chemical synthesis. Its applications range from preparing analytical standards for biological assays to use in studies involving vascular smooth muscle cell function.
- IUPAC
- Malonaldehyde bis(dimethyl acetal)
- Synonyms
- 3-TetramethoxypropaneMalonaldehyde bis(dimethyl acetal)1,1,3,3-Tetramethoxypropane, 99%(CH3O)2CHCH2CH(OCH3)2

Malondialdehyde Standard Preparation
1,1,3,3-Tetramethoxypropane is employed in the preparation of malondialdehyde (MDA) standards. These standards are crucial for accurately quantifying MDA levels in biological samples, such as lung homogenates, during malondialdehyde assays.
Research in Vascular Biology
This compound has been utilised in research settings to investigate the effects of specific agents, like Salvianolic acid A, on the migration and proliferation of vascular smooth muscle cells, contributing to the understanding of cardiovascular processes.
Organic Synthesis Building Block
As a functionalised acetal, 1,1,3,3-Tetramethoxypropane acts as a valuable building block in organic synthesis. It can be used to introduce specific functional groups or carbon frameworks in the construction of more complex molecules.
| Molecular weight | 164.20 |
|---|---|
| Linear formula | (CH3O)2CHCH2CH(OCH3)2 |
| Assay | 99% |
| Boiling point | 183 °C(lit.)70-75 °C/15 mmHg(lit.) |
| Density | 0.997 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.407(lit.) |
| Application | 1,1,3,3-Tetramethoxypropane was used in preparing malondialdehyde standards during malondialdehyde assay on lung homogenates1. It was used to study the effect of Salvianolic acid A on the migration and proliferation of vascular smooth muscle cells2. |

Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 54 °C / 129.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,1,3,3-Tetramethoxypropane used for?
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1,1,3,3-Tetramethoxypropane is used as a building block in chemical synthesis, for preparing malondialdehyde standards in biological assays, and in studies related to vascular smooth muscle cell function.
What are the CAS number and formula for 1,1,3,3-Tetramethoxypropane?
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The CAS number for 1,1,3,3-Tetramethoxypropane is 102-52-3, and its linear formula is (CH3O)2CHCH2CH(OCH3)2.
What grade and purity does Tech Serve Solutions supply for 1,1,3,3-Tetramethoxypropane?
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Tech Serve Solutions supplies 1,1,3,3-Tetramethoxypropane with an assay of 99%. This is considered a high-purity grade suitable for research and synthesis. TSS does not represent this product as USP, BP, or EP grade.
How should 1,1,3,3-Tetramethoxypropane be handled safely?
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1,1,3,3-Tetramethoxypropane is a flammable liquid and vapour (H226). Handle with care in a well-ventilated area, away from ignition sources. Appropriate personal protective equipment, including eyeshields and gloves, should be worn. Refer to the Safety Data Sheet for full handling instructions.
Is 1,1,3,3-Tetramethoxypropane a controlled substance?
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The provided data does not indicate that 1,1,3,3-Tetramethoxypropane is a controlled substance.
How is 1,1,3,3-Tetramethoxypropane packed and exported?
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1,1,3,3-Tetramethoxypropane is packed according to relevant transport regulations, including UN 1993 C3/PGIII classification for shipping. TSS exports globally, adhering to all international shipping and customs requirements.
How can I request a sample or quote for 1,1,3,3-Tetramethoxypropane?
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To request a sample or a quote for 1,1,3,3-Tetramethoxypropane, please contact our sales team through the website or by phone, providing your specific requirements.
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