Tetramethylammonium hydroxide pentahydrate
Tetramethylammonium hydroxide pentahydrate (CAS 10424-65-4) is a strong organic base supplied by Tech Serve Solutions. With the linear formula (CH₃)₄N(OH) · 5H₂O and a molecular weight of 181.23 g/mol, it is a crystalline solid. This compound is primarily utilised as a strong base in organic synthesis, a phase-transfer catalyst, and in the production of certain electronic materials and ionic liquids.

Organic Synthesis
Tetramethylammonium hydroxide pentahydrate serves as a potent base in various organic reactions, facilitating deprotonations and other base-catalyzed transformations. Its solubility in organic solvents makes it a versatile reagent for synthesizing complex molecules.
Phase-Transfer Catalysis
As a quaternary ammonium salt, it can act as a phase-transfer catalyst, enabling reactions between reactants located in different immiscible phases. This enhances reaction rates and yields in heterogeneous reaction systems.
Electronics Manufacturing
This compound finds application in the microelectronics industry, particularly in photolithography processes as a developer or etchant. Its controlled reactivity is crucial for precise pattern formation on semiconductor wafers.
Ionic Liquid Precursor
Tetramethylammonium hydroxide can be used in the synthesis of certain ionic liquids. These unique salts exhibit a wide range of properties suitable for applications such as electrolytes, solvents, and catalysts.
| Molecular weight | 181.23 |
|---|---|
| Linear formula | (CH3)4N(OH) · 5H2O |
| Assay | ≥95.0% (T) |
| Vapour density | 1.1 (vs air) |
| Autoignition temp | 878 °F |
| Impurities tested | ≤0.1% halides (as chloride) |
| Melting point | 67-70 °C(lit.) |


Hazard statements
- H300Fatal if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3423 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 24/25-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Anion traces | sulfate (SO42-): ≤1000 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 36 % |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylammonium hydroxide pentahydrate used for?
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Tetramethylammonium hydroxide pentahydrate is used as a strong organic base in chemical synthesis, as a phase-transfer catalyst, in the electronics industry for photolithography, and as a precursor for ionic liquids.
What is the CAS number and formula for Tetramethylammonium hydroxide pentahydrate?
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The CAS number is 10424-65-4 and the linear formula is (CH₃)₄N(OH) · 5H₂O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylammonium hydroxide pentahydrate with an assay of ≥95.0% (T). TSS does not represent this product as USP, BP, or EP grade.
How should Tetramethylammonium hydroxide pentahydrate be handled safely?
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Tetramethylammonium hydroxide pentahydrate is corrosive and toxic. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection. Avoid ingestion and skin/eye contact. Refer to the Safety Data Sheet for detailed handling instructions.
Is Tetramethylammonium hydroxide pentahydrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Tetramethylammonium hydroxide pentahydrate.
How can I request a sample or quote for Tetramethylammonium hydroxide pentahydrate?
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Please contact the Tech Serve Solutions sales team through our website or by phone to request a sample or a quotation for Tetramethylammonium hydroxide pentahydrate.
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