SU 5416
SU 5416 (CAS: 204005-46-9) is a chemical compound with the formula C15H14N2O and a molecular weight of 238.28 g/mol. Supplied by Tech Serve Solutions with an assay of ≥98% (HPLC), this yellow to yellow-orange substance is primarily utilised in biological research. It serves as an important tool for investigating angiogenesis, particularly in studies involving zebrafish and mouse models of pulmonary arterial hypertension, and in understanding cell signaling pathways.
- IUPAC
- 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one
- Synonyms
- 1,3-Dihydro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-2H-indol-2-one
Angiogenesis Research
SU 5416 has been employed in studies to investigate the mechanisms underlying cerebral and pulmonary vascular development. Its use in zebrafish hindbrain and mouse models of pulmonary arterial hypertension aids in understanding these complex biological processes.
Cell Biology and Signaling
This compound is valuable for research in cell biology, particularly in the study of cell signaling pathways. It acts as an angiogenesis inhibitor, providing insights into signal transduction relevant to various cellular functions.
Biochemical Research Tool
As a bioactive small molecule, SU 5416 serves as a research reagent for biochemical investigations. Its specific activity makes it useful for exploring enzyme inhibition and related biological mechanisms.
| Molecular weight | 238.28 |
|---|---|
| Empirical formula | C15H14N2O |
| Assay | ≥98% (HPLC) |
| Colour | yellow to yellow orange |
| Solubility | H2O: insoluble |
| Storage temperature | −20°C |
| Application | SU 516 was used to study the mechanism of development of cerebral vasculature in zebrafish hindbrain.3 It was used to study the pulmonary vascular remodeling in response to hypoxia in mouse model of pulmonary arterial hypertension.4 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SU 5416 used for?
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SU 5416 is used in scientific research, primarily for studying angiogenesis, including its development in zebrafish and its role in pulmonary arterial hypertension. It is also used in cell biology research to investigate cell signaling and as an enzyme inhibitor.
What are the CAS number and formula for SU 5416?
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The CAS number for SU 5416 is 204005-46-9, and its molecular formula is C15H14N2O.
What grade and purity does Tech Serve Solutions supply for SU 5416?
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Tech Serve Solutions supplies SU 5416 with a purity of ≥98% as determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should SU 5416 be handled safely?
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SU 5416 is classified as a Warning substance, with hazard statements indicating it causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). When handling, use a dust mask type N95, eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
How is SU 5416 packed, shipped, and exported by TSS?
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SU 5416 is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions. Specific packaging details can be provided upon request.
How can I request a sample or quote for SU 5416?
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To request a sample or a quote for SU 5416, please contact the Tech Serve Solutions sales team via our website or by phone. Provide your specific requirements, and we will respond promptly.
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