Sodium taurocholate hydrate
Sodium taurocholate hydrate (CAS 345909-26-4), with a molecular weight of 537.68 on an anhydrous basis (C26H44NNaO7S · xH2O), is an anionic detergent and a bile salt. It functions effectively as an emulsifier in biochemical research and cell culture applications. Its properties make it valuable for membrane protein solubilization and in various chromatography techniques. TSS supplies this compound for laboratory and research purposes.
- IUPAC
- 2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid,3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide,Sodium taurocholate hydrate
- Synonyms
- Sodium taurocholate hydrate2-[(3α,7α,12α-Trihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid, sodium salt hydrate3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide, sodium salt hydrate
Emulsifier in Biological Assays
Sodium taurocholate hydrate serves as an effective emulsifier. It has been utilised in the <i>in situ</i> preparation of digestive enzymes, facilitating their functional analysis in research settings.
Membrane Protein Solubilization
As a bile salt and anionic detergent, this compound is employed in the solubilization of membrane proteins. Its amphipathic nature aids in maintaining protein structure during extraction and purification.
Chromatography Applications
This bile acid derivative is applicable in various chromatography techniques, including electrophoresis and others requiring specific lipid or detergent interactions for separation.
Cell Culture Reagent
Sodium taurocholate hydrate can be used as a component in specific cell culture media formulations, supporting research involving cellular processes and lipid metabolism.
| Molecular weight | 537.68 (anhydrous basis) |
|---|---|
| Empirical formula | C26H44NNaO7S · xH2O |
| Assay | ≥95% (TLC) |
| Solubility | H2O: soluble0.2 M, clear, colorless to faintly yellow |
| Optical activity | [α]20/D +23±1°, c = 3% in H2O (dry matter) |
| Impurities tested | ≤0.005% Phosphorus (P)≤0.1% Insoluble matter |
| Application | Sodium taurocholate hydrate was used as an emulsifier in in situ preparation of digestive enzymes.1 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Al: ≤0.0005%Ca: ≤0.005%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.01%Mg: ≤0.005%NH4+: ≤0.1%Pb: ≤0.001%Zn: ≤0.0005% |
| Anion traces | chloride (Cl-): ≤0.05%sulfate (SO42-): ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | anionic |
|---|---|
| Aggregation Number | 4 |
| Cmc | 3-11 mM(20-25°C) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sodium taurocholate hydrate used for?
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Sodium taurocholate hydrate is primarily used as an anionic detergent and emulsifier in biochemical research, including applications such as the preparation of digestive enzymes, membrane protein solubilization, and in chromatography and cell culture.
What are the CAS number and chemical formula for Sodium taurocholate hydrate?
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The CAS number for Sodium taurocholate hydrate is 345909-26-4. The empirical formula (anhydrous basis) is C26H44NNaO7S, and it is supplied as a hydrate (· xH2O).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium taurocholate hydrate with an assay of ≥95% (TLC). TSS does not represent this product as USP, BP, or EP grade.
How should Sodium taurocholate hydrate be handled safely?
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Handling Sodium taurocholate hydrate requires appropriate personal protective equipment, including eyeshields and gloves. For airborne particles, a type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet for full details.
How is Sodium taurocholate hydrate packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details for Sodium taurocholate hydrate are available upon request, adhering to international shipping regulations.
How can I request a sample or quote for Sodium taurocholate hydrate?
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To request a sample or a quote for Sodium taurocholate hydrate, please contact the Tech Serve Solutions sales team via our website or direct contact details.
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