Sodium methoxide solution
Sodium methoxide solution (CAS: 124-41-4, Formula: CH3ONa, MW: 54.02 g/mol) is a strong organic base supplied by Tech Serve Solutions. This solution, typically 0.5 M in methanol, is a versatile reagent essential for numerous organic syntheses. It is widely employed as a catalyst and reactant in esterification, transesterification, and condensation reactions, finding applications in pharmaceuticals, biodiesel production, and fine chemical manufacturing.
- IUPAC
- Sodium methylate

Organic Synthesis Reagent
Sodium methoxide serves as a potent base and nucleophile in various organic transformations. It is particularly effective in promoting condensation reactions, alkylations, and dehydrohalogenations.
Biodiesel Production
This compound is a key catalyst in the transesterification of triglycerides with methanol to produce fatty acid methyl esters (biodiesel). Its high basicity facilitates the reaction efficiently.
Pharmaceutical Intermediates
It is extensively used in the synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs) and their precursors. Its reactivity profile makes it indispensable in multi-step synthetic routes.
Catalyst for Polymerisation
Sodium methoxide can act as an initiator or catalyst in certain polymerisation processes, contributing to the synthesis of specific polymeric materials.
| Molecular weight | 54.02 |
|---|---|
| Linear formula | CH3ONa |
| Assay | ≥97.0% (T) |
| Grade | ACS reagent |
| Colour | , clarity of solution to pass |
| Boiling point | 64.6 °C |
| Density | 0.81 g/mL at 20 °C |
| Refractive index | n20/D 1.37 |
| Concentration | 0.5 M in methanol |
| Vapour pressure | 50 mmHg (20 °C) |
| Vapour density | 1.1 (vs air) |
| Autoignition temp | 851 °F |
| Impurities tested | ~2% Na2CO3 and NaOH |




Hazard statements
- H226Flammable liquid and vapour
- H251Self-heating; may catch fire
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H331Toxic if inhaled
- H370Causes damage to organs
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P235Keep cool
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1289 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-23/24/25-39/23/24/25 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is sodium methoxide solution used for?
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Sodium methoxide solution is a strong organic base primarily used as a catalyst and reactant in organic synthesis, including esterification, transesterification (e.g., for biodiesel production), and condensation reactions. It is also employed in the synthesis of pharmaceutical intermediates and in materials science.
What is the CAS number and formula for sodium methoxide solution?
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The CAS number for sodium methoxide is 124-41-4, and its chemical formula is CH3ONa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sodium Methoxide Solution at an ACS reagent grade, with an assay of ≥97.0% (T) and a concentration of 0.5 M in methanol. We do not represent this product as USP, BP, or EP grade.
How should sodium methoxide solution be handled?
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Sodium methoxide solution is highly flammable, corrosive, and toxic. It requires careful handling with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area. Avoid contact with skin, eyes, and inhalation of vapours. Refer to the Safety Data Sheet for detailed guidance.
Is sodium methoxide solution exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including sodium methoxide solution.
How can I request a quote or sample?
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To request a quote or a sample of sodium methoxide solution, please contact our sales team via the details provided on our website.
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