Sodium glycocholate hydrate

CAS 338950-81-5C26H42NO6Na · xH2OBiochemicals & Reagents

Sodium glycocholate hydrate (CAS: 338950-81-5; Formula: C26H42NO6Na · xH2O; Molar Mass: 487.60 g/mol anhydrous basis) is an anionic bile salt. It functions as a biological detergent, critical in biochemical research for solubilising membrane proteins and in cell culture applications. Its amphipathic nature makes it valuable for stabilising emulsions and liposomes in various laboratory settings.

IUPAC: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide sodium salt,Glycocholic acid sodium salt hydrate,N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)glycine sodium salt,N-Cholylglycine sodium salt
Synonyms: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide sodium saltGlycocholic acid sodium salt hydrateN-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)glycine sodium saltN-Cholylglycine sodium salt

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Sodium glycocholate hydrate (C26H42NO6Na · xH2O) — chemical structure, CAS 338950-81-5; Life Science, fine chemical supplied by Tech Serve Solutions

Anionic DetergentsAntigen-Vaccine PreparationBile SaltsBiochemicals and ReagentsCell CultureCore BioreagentsDetergentsDetergents N to ZDetergents by ApplicationsResearch Essentials More...

01 /Applications

Detergent in Biochemical Assays

Utilised for its anionic detergent properties in various biochemical assays. It aids in the solubilisation of membrane proteins and lipids, facilitating their study and purification.

Cell Culture Supplement

Can be used as a component in specific cell culture media formulations. Its role is often related to modulating membrane properties or providing essential biological components.

Liposome and Emulsion Stabilisation

Its amphipathic structure makes it effective in stabilising liposomes and emulsions. This is beneficial in research involving drug delivery systems or in vitro diagnostics.

Antigen and Vaccine Preparation

Employed in the preparation and formulation of antigens and vaccines. It can assist in the solubilisation or stabilisation of immunogenic components.

02 /Properties

Molecular weight	487.60 (anhydrous basis)
Linear formula	C26H42NO6Na · xH2O
Assay	≥97.0% (calc. based on dry substance, NT)
Optical activity	[α]20/D +28.0±1°, c = 2% in H2O (dry matter)
Loss on drying	≤10% loss on drying
Impurities tested	≤1% cholic acid (TLC)
Application	Do you have application information on this product that you would like to share?
Melting point	210-215 °C (subl.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Cation traces	Ca: ≤100 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤5000 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

338950-81-5

MDL number

MFCD09037360

PubChem substance

24895292

Beilstein registry

3854517

05 /Additional specifications

Description	anionic
Mol Wt	micellar avg mol wt 1000average mol wt 1000
Aggregation Number	2
Cmc	7 mM(20-25°C)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Sodium glycocholate hydrate used for?

Sodium glycocholate hydrate is used as an anionic detergent in biochemical assays, a supplement in cell culture, for stabilising liposomes and emulsions, and in antigen and vaccine preparation.

What is the CAS number and chemical formula for Sodium glycocholate hydrate?

The CAS number is 338950-81-5 and the chemical formula is C26H42NO6Na · xH2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Sodium glycocholate hydrate with an assay of ≥97.0% (calc. based on dry substance, NT). This product is not supplied as USP, BP, EP, or pharmacopoeia grade.

How should Sodium glycocholate hydrate be handled?

When handling Sodium glycocholate hydrate, wear appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Dispose of according to local regulations.

Is Sodium glycocholate hydrate a controlled substance?

The provided data does not indicate that Sodium glycocholate hydrate is a controlled substance.

How is Sodium glycocholate hydrate shipped and exported?

Tech Serve Solutions, a specialist global supplier and exporter since 1998, ships and exports Sodium glycocholate hydrate worldwide, adhering to all necessary regulations for chemical transport.