(R)(−)-α-Methylhistamine dihydrochloride
(R)(−)-α-Methylhistamine dihydrochloride (CAS: 75614-89-0), with the molecular formula C6H11N3 · 2HCl and a molecular weight of 198.09 g/mol, is a white to off-white solid. This compound is known for its utility as an agonist in research settings, particularly within cell signaling and neuroscience. It is soluble in water and typically supplied with a purity of ≥98% (HPLC), making it suitable for various laboratory applications.
- IUPAC
- (R)(−)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride
- Synonyms
- (R)(−)-α-Methylhistamine dihydrochloride(R)-alpha-Methylhistamine dihydrochloride(R)-2-(1H-imidazol-4-yl)propan-1-amine dihydrochloride
Neuroscience Research
This compound serves as a valuable tool in neuroscience research, acting as an agonist to investigate neurotransmission and cellular signaling pathways. Its specific activity relates to histamine receptors, contributing to studies on brain function and neurological disorders.
GPCR Modulation Studies
As a modulator of G protein-coupled receptors (GPCRs), (R)(−)-α-Methylhistamine dihydrochloride is utilized in studies focused on receptor function and downstream signaling. This is crucial for understanding cellular responses to various stimuli.
Cell Biology Investigations
Researchers employ this chemical in cell biology to explore mechanisms related to cell signaling and response. Its defined biological activity makes it useful for dissecting complex cellular processes.
| Molecular weight | 198.09 |
|---|---|
| Empirical formula | C6H11N3 · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: soluble |
| Optical activity | [α]22/D −4°, c = 0.8 in H2O(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HRH3(11255) |
|---|---|
| Storage Condition | desiccated |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)(−)-α-Methylhistamine dihydrochloride used for?
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(R)(−)-α-Methylhistamine dihydrochloride is primarily used in research as an agonist, particularly in the fields of neuroscience and cell biology, for studying neurotransmission, cell signaling, and GPCR modulation.
What is the CAS number and formula for (R)(−)-α-Methylhistamine dihydrochloride?
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The CAS number is 75614-89-0 and the molecular formula is C6H11N3 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)(−)-α-Methylhistamine dihydrochloride with a purity of ≥98% (HPLC). This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should (R)(−)-α-Methylhistamine dihydrochloride be handled and stored?
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Handle (R)(−)-α-Methylhistamine dihydrochloride with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, as it may cause skin, eye, and respiratory irritation (H315, H319, H335). Store in a desiccated state to maintain stability.
Is (R)(−)-α-Methylhistamine dihydrochloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals like (R)(−)-α-Methylhistamine dihydrochloride.
How can I request a sample or quote for (R)(−)-α-Methylhistamine dihydrochloride?
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Please contact our sales team through the website to request a sample or a formal quotation for (R)(−)-α-Methylhistamine dihydrochloride.
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