(R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine
(R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine (CAS: 23357-46-2) is a chiral amine with the molecular formula (C10H11)NH2 and a molecular weight of 147.22 g/mol. It serves as a valuable building block in asymmetric synthesis and organic chemistry. Its defined stereochemistry makes it crucial for developing stereoselective reactions and synthesizing complex chiral molecules for research and development purposes.
- IUPAC
- (R)-(−)-1-AminoTetralin®,(R)-(−)-1-Aminotetraline,(R)-1,2,3,4-Tetrahydro-1-naphthylamine
- Synonyms
- (R)-(−)-1-AminoTetralin(R)-(−)-1-Aminotetraline4-Tetrahydro-1-naphthylamine(C10H11)NH2

Chiral Building Block
Utilised in the synthesis of enantiomerically pure compounds. Its specific (R)-configuration is essential for creating chiral targets in pharmaceutical and agrochemical research.
Asymmetric Synthesis
Serves as a chiral auxiliary or precursor in stereoselective reactions. It aids in controlling the stereochemical outcome of reactions, leading to desired enantiomers.
Organic Synthesis Intermediate
A versatile intermediate in multi-step organic synthesis. It can be functionalised further to create a range of complex organic molecules for various research applications.
| Molecular weight | 147.22 |
|---|---|
| Linear formula | (C10H11)NH2 |
| Assay | ≥98.5% (GC) |
| Boiling point | 118-120 °C/10 mbar |
| Density | 1.002 g/mL at 25 °C |
| Refractive index | n20/D 1.565 |
| Optical purity | enantiomeric excess: ≥98.5% |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36/37/38-51/53 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine primarily used for?
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(R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine is primarily used as a chiral building block and intermediate in asymmetric synthesis and organic chemistry research.
What are the CAS number and chemical formula for (R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine?
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The CAS number is 23357-46-2, and the chemical formula is (C10H11)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(−)-1,2,3,4-Tetrahydro-1-naphthylamine with an assay of ≥98.5% (GC) and optical purity of enantiomeric excess ≥98.5%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the main safety hazards associated with this chemical?
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This compound is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), may cause respiratory irritation (H335), and is toxic to aquatic life with long lasting effects (H411). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used.
How is this chemical packed and shipped?
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Tech Serve Solutions ensures secure packaging suitable for export, adhering to international shipping regulations for hazardous materials, including UN 3082, Class 9, Packing Group III.
How can I request a sample or quote?
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To request a sample or obtain a quote, please use the contact form on our website or email our sales department directly, referencing the product name and CAS number.
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