ARL 67156 trisodium salt hydrate
ARL 67156 trisodium salt hydrate (CAS 160928-38-1) is a dibromomethylene adenosine triphosphate analogue with the empirical formula C15H21Br2N5Na3O12P3 · xH2O and a molecular weight of 785.05 (anhydrous basis). This bioactive small molecule is primarily utilised in cell biology and neuroscience research, particularly for investigating ecto-ATPases and neurotransmission pathways. Its specific structure makes it a valuable tool for probing enzyme activity and cellular signalling mechanisms.
- IUPAC
- 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate trisodium salt hydrate,FPL 67156
- Synonyms
- 6-N,N-Diethyl-β-γ-dibromomethylene-D-adenosine-5′-triphosphate trisodium salt hydrate,FPL 67156
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Enzyme Inhibition Studies
ARL 67156 trisodium salt hydrate serves as a selective inhibitor of ecto-ATPases, making it invaluable for research into cellular energy metabolism and signalling pathways dependent on extracellular ATP hydrolysis. It allows scientists to investigate the roles of these enzymes in various physiological and pathological processes.
Neuroscience Research
This compound is employed in neuroscience to study neurotransmission and the function of ecto-nucleotidases in the central nervous system. By inhibiting ATP breakdown, it helps elucidate the extracellular purinergic signalling cascades involved in neuronal communication and function.
Cell Biology Investigations
As a tool in cell biology, ARL 67156 trisodium salt hydrate aids in understanding cellular responses to extracellular ATP. It can be used to probe the effects of ecto-ATPase activity on cell proliferation, migration, and other fundamental cellular processes.
| Molecular weight | 785.05 (anhydrous basis) |
|---|---|
| Empirical formula | C15H21Br2N5Na3O12P3 · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: >20 mg/mLDMSO: insoluble |
| Storage temperature | −20°C |
| Gene Information | human ... ENTPD2(954) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is ARL 67156 trisodium salt hydrate used for?
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ARL 67156 trisodium salt hydrate is used as a research chemical, primarily for studying ecto-ATPases, cell signalling, neurotransmission, and neurotransmitter metabolism, particularly in the fields of cell biology and neuroscience.
What are the CAS number and formula for ARL 67156 trisodium salt hydrate?
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The CAS number for the free acid is 160928-38-1. The empirical formula is C15H21Br2N5Na3O12P3 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies ARL 67156 trisodium salt hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for ARL 67156 trisodium salt hydrate?
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ARL 67156 trisodium salt hydrate is classified under WGK Germany 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area. Avoid release into the environment.
How is ARL 67156 trisodium salt hydrate supplied and exported?
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ARL 67156 trisodium salt hydrate is typically supplied as a white to off-white solid and stored at −20°C. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals.
How can I request a quote or sample for ARL 67156 trisodium salt hydrate?
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To request a quote or sample, please contact our sales team through the website or by phone. Specify the product name and CAS number for prompt service.
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