PTH-isoleucine
3-Phenyl-2-thiohydantoic acid isoleucine derivative (PTH-isoleucine) is a chemical compound with the CAS number 5066-94-4 and molecular formula C13H16N2OS. It has a molecular weight of 248.34 g/mol. This compound is primarily utilised in the fields of molecular biology and protein sequencing for structural analysis and proteomics research, serving as a key reagent in these scientific disciplines.

Protein Sequencing
PTH-isoleucine is a critical reagent used in the Edman degradation process for the sequential identification of amino acids in a protein or peptide. It aids in the determination of N-terminal amino acid residues, facilitating the elucidation of protein primary structures.
Protein Structural Analysis
As a derivative employed in protein sequencing, this compound contributes to the broader field of protein structural analysis by providing fundamental data on amino acid composition and order.
Proteomics Research
In proteomics, PTH-isoleucine serves as a valuable tool for understanding protein identity and modifications. Its application in sequencing supports the comprehensive study of proteomes.
Molecular Biology Applications
This compound finds use in various molecular biology workflows that require precise protein characterisation. It is instrumental in research involving protein identification and functional studies.
| Molecular weight | 248.34 |
|---|---|
| Empirical formula | C13H16N2OS |
| Storage temperature | −20°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PTH-isoleucine used for?
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PTH-isoleucine is a reagent primarily used in protein sequencing, protein structural analysis, proteomics research, and other molecular biology applications. It is particularly important for determining N-terminal amino acid residues.
What are the CAS number and formula for PTH-isoleucine?
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The CAS number for PTH-isoleucine is 5066-94-4, and its empirical formula is C13H16N2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies PTH-isoleucine primarily for research and laboratory use. The specific assay and purity are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling PTH-isoleucine?
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According to GHS classifications, PTH-isoleucine is harmful if swallowed and causes skin irritation and serious eye irritation. Appropriate personal protective equipment, including gloves and eye protection, should be worn during handling. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive safety information.
How is PTH-isoleucine shipped and exported?
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Tech Serve Solutions can pack and export PTH-isoleucine globally. Please contact our sales team to discuss specific shipping and export requirements for your region.
How can I request a quote or sample for PTH-isoleucine?
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To request a quote or a sample of PTH-isoleucine, please visit the product page on our website and use the 'Request Quote' or 'Request Sample' functions, or contact our customer service department directly.
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