PTH-alanine
N-Phenylthiocarbamoyl-L-alanine (PTH-alanine), CAS 4333-19-1, with the molecular formula C10H10N2OS and a molecular weight of 206.26 g/mol, is a derivative of alanine. It is primarily employed in biochemical research, specifically within the fields of protein sequencing and structural analysis. This compound serves as a crucial reagent in the Edman degradation process for identifying amino acid sequences in peptides and proteins, contributing to advancements in proteomics and molecular biology.
Protein Sequencing
PTH-alanine is utilized as a reagent in automated protein sequencing techniques, such as the Edman degradation method. It enables the stepwise identification of amino acids from the N-terminus of a peptide chain.
Proteomics Research
In the study of proteomics, this compound aids in the characterisation of proteins and their modifications. Its application is vital for understanding protein function and biological pathways.
Protein Structural Analysis
PTH-alanine contributes to determining the primary structure of proteins, which is fundamental for understanding their three-dimensional conformation and biological activity.
Molecular Biology Reagent
As a specialised reagent, it supports various molecular biology applications that involve the analysis of protein composition and sequence integrity.
| Molecular weight | 206.26 |
|---|---|
| Empirical formula | C10H10N2OS |
| Storage temperature | −20°C |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is PTH-alanine primarily used for?
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PTH-alanine is primarily used as a reagent in protein sequencing, particularly in Edman degradation, for identifying amino acid sequences and in broader proteomics and protein structural analysis research.
What are the CAS number and molecular formula for PTH-alanine?
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The CAS number for PTH-alanine is 4333-19-1, and its molecular formula is C10H10N2OS.
What grade and purity does Tech Serve Solutions supply for PTH-alanine?
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Tech Serve Solutions supplies PTH-alanine. The specific grade and purity are available upon request; it is not represented as USP, BP, or EP grade.
How should PTH-alanine be handled safely?
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PTH-alanine is acutely toxic if swallowed, in contact with skin, or if inhaled. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation and follow all safety precautions. It is classified as Danger, with hazard statements H301 + H311 + H331.
How is PTH-alanine packed and shipped?
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PTH-alanine is packed and shipped in accordance with international regulations for hazardous materials, identified under UN 2811 (Toxic solid, organic, n.o.s.) with Packing Group III. Storage temperature is typically -20°C.
How can I request a quote or sample of PTH-alanine?
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To request a quote or sample of PTH-alanine, please contact our sales team through the website or by phone, providing your details and the quantity required.
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