Potassium bis(trimethylsilyl)amide

CAS 40949-94-8[(CH3)3Si]2NKAcids & Bases

Potassium bis(trimethylsilyl)amide (CAS: 40949-94-8) is a potent organic base with the formula [(CH3)3Si]2NK and a molecular weight of 199.48 g/mol. This sterically hindered compound is valued in organic synthesis for its utility as an anionic initiator and a selective base. It plays a role in the preparation of polymers like poly(ethylene oxide) and the synthesis of various metal complexes.

IUPAC: Hexamethyldisilazane potassium salt,Potassium hexamethyldisilazide
Synonyms: Hexamethyldisilazane potassium saltPotassium hexamethyldisilazide

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Potassium bis(trimethylsilyl)amide ([(CH3)3Si]2NK) — chemical structure, CAS 40949-94-8; Chemistry, fine chemical supplied by Tech Serve Solutions

Acids & BasesBasesChemical SynthesisOrganic BasesSynthetic Reagents

01 /Applications

Anionic Polymerisation Initiator

Used in the preparation of poly(ethylene oxide), facilitating controlled polymer chain growth. Its strong basicity makes it effective for initiating anionic polymerisation reactions.

Selective Base in Organic Synthesis

Employed as a sterically hindered base to promote selective cyclization reactions. Its unique structure allows for controlled deprotonation, minimising unwanted side reactions.

Ligand for Metal Complex Synthesis

Utilised in the preparation of lanthanide complexes. It acts as a ligand, coordinating with metal ions to form stable complexes with specific catalytic or material properties.

02 /Properties

Molecular weight	199.48
Linear formula	[(CH3)3Si]2NK
Assay	95%
Density	0.915 g/mL at 25 °C
Concentration	1 M in THF
Vapour density	3.2 (vs air)
Application	Anionic initiator used in the preparation of poly(ethylene oxide).1 Sterically hindered base employed in selective cyclization reactions.2 Also used in the preparation of lanthanide complexes.3,4

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3263 8 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	14-34
Safety statements (S)	26-36/37/39-43-45
Supplemental hazards	Reacts violently with water.

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

40949-94-8

MDL number

MFCD00010330

PubChem substance

24859460

Beilstein registry

4006754

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Potassium bis(trimethylsilyl)amide used for?

Potassium bis(trimethylsilyl)amide is an anionic initiator for poly(ethylene oxide) preparation, a sterically hindered base for selective cyclisation reactions, and is used in the synthesis of lanthanide complexes.

What is the CAS number and formula for Potassium bis(trimethylsilyl)amide?

The CAS number is 40949-94-8, and the chemical formula is [(CH3)3Si]2NK.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Potassium bis(trimethylsilyl)amide with an assay of 95%. This product is typically supplied as a technical or research grade, and TSS does not represent it as USP, BP, or EP grade.

How should Potassium bis(trimethylsilyl)amide be handled safely?

Potassium bis(trimethylsilyl)amide is a corrosive substance that reacts violently with water, causing severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eyeshields, and a face shield. Ensure adequate ventilation and avoid contact with water.

How is this chemical packed, shipped, and exported?

This chemical is packed in compliance with UN 3263, Class 8, PGIII regulations. Tech Serve Solutions exports globally, adhering to all international shipping and handling standards for hazardous materials.

How can I request a sample or quote for Potassium bis(trimethylsilyl)amide?

To request a sample or quote, please contact our sales team via the website or direct email, providing your specific requirements and delivery details.