Picrylsulfonic acid solution
Picrylsulfonic acid solution (CAS: 2508-19-2, C6H3N3O9S, MW: 293.17) is a hydrophilic modifying reagent supplied by Tech Serve Solutions. It is particularly suitable for the determination of primary amines. The solution is prepared at a 5% (w/v) concentration in water and requires storage at 2-8°C. This compound finds applications in general protein quantitation and molecular biology due to its reactivity with amino compounds.
- IUPAC
- 2,4,6-Trinitrobenzenesulfonic acid solution,TNBS

Determination of Primary Amines
Picrylsulfonic acid solution is a hydrophilic modifying reagent that reacts with primary amines. Derivatives formed with amino compounds can be regenerated using hydrazine.
General Protein Quantitation
This reagent is utilised in general protein quantitation methods. Its reactivity with amino groups makes it suitable for biochemical assays.
Molecular Biology Applications
Within molecular biology, picrylsulfonic acid solution can be employed for specific derivatisation reactions involving amino functionalities.
| Molecular weight | 293.17 |
|---|---|
| Empirical formula | C6H3N3O9S |
| Concentration | 5 % (w/v) in H2O |
| Storage temperature | 2-8°C |
| Application | Hydrophilic modifying reagent.1 Derivatives with amino compounds can be regenerated with hydrazine.2 |
| Suitability | suitable for determination of primary amines |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3265 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 1-22-36/38-43 |
| Safety statements (S) | 26-35-36/37 |
| Supplemental hazards | Explosive when dry. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Picrylsulfonic acid solution used for?
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Picrylsulfonic acid solution is primarily used as a hydrophilic modifying reagent for the determination of primary amines. It is also applied in general protein quantitation and molecular biology.
What are the CAS number and formula for Picrylsulfonic acid solution?
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The CAS number for Picrylsulfonic acid solution is 2508-19-2, and its empirical formula is C6H3N3O9S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Picrylsulfonic acid solution as a 5% (w/v) concentration in H2O. This product is suitable for research and technical applications. Tech Serve Solutions does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product specifications.
What are the safety and handling considerations for Picrylsulfonic acid solution?
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Picrylsulfonic acid solution is classified as dangerous goods. It is harmful if swallowed (H302), causes severe skin burns and eye damage (H314), and may cause an allergic skin reaction (H317). It is also explosive when dry. Handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C.
How is Picrylsulfonic acid solution shipped and exported by TSS?
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Picrylsulfonic acid solution is shipped and exported as UN 3265, Class 8, Packing Group II, indicating it is a corrosive solid, acidic, organic, n.o.s. (Picrylsulfonic acid solution). TSS adheres to all international shipping regulations for hazardous materials.
How can I request a sample or quote for Picrylsulfonic acid solution?
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To request a sample or a quotation for Picrylsulfonic acid solution, please contact our sales department via the website or email, providing your specific requirements and delivery details.
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