Penfluridol
Penfluridol (CAS 26864-56-2) is a white, crystalline powder with the molecular formula C28H27ClF5NO and a molecular weight of 523.97. It is primarily recognised as a diphenylbutylpiperidine long-acting antipsychotic, functioning as a voltage-gated calcium channel modulator and inhibitor. Utilised in neuroscience research, it serves as a valuable tool for studying ion channel function and neuronal signaling pathways.
- IUPAC
- 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3(trifluoromethyl)phenyl]-4-piperidinol,R16341

Neuroscience Research Tool
Penfluridol is employed in scientific research to investigate the intricate mechanisms of the central nervous system. Its activity as a calcium channel modulator makes it useful for studying neuronal excitability and neurotransmission.
Ion Channel Studies
As a modulator of voltage-gated calcium channels, Penfluridol aids researchers in understanding the role of these channels in various physiological and pathological processes within the nervous system.
Bioactive Small Molecule
This compound is classified as a bioactive small molecule, making it a subject of interest in drug discovery and development programmes exploring potential therapeutic applications.
| Molecular weight | 523.97 |
|---|---|
| Empirical formula | C28H27ClF5NO |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | DMSO: >20 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Penfluridol used for?
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Penfluridol is used in neuroscience research as a tool to study voltage-gated calcium channels and their role in neuronal signaling. It is also classified as a bioactive small molecule.
What is the CAS number and formula for Penfluridol?
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The CAS number for Penfluridol is 26864-56-2, and its empirical formula is C28H27ClF5NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Penfluridol with a purity of ≥98% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety concerns when handling Penfluridol?
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Penfluridol is classified as Danger with hazard statement H301 (Toxic if swallowed). Appropriate personal protective equipment including eyeshields, faceshields, gloves, and a P2 respirator is essential. Handle with extreme caution and follow all safety protocols.
How is Penfluridol shipped and exported?
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Penfluridol is shipped and exported in compliance with international regulations, identified as UN 2811, Class 6.1, Packing Group III. Storage is recommended at 2-8°C.
How can I request a sample or quote for Penfluridol?
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To request a sample or quote for Penfluridol, please contact the Tech Serve Solutions sales team via our website or direct enquiry channels.
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