O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol
O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol (CAS: 866889-02-3; Formula: C19H38O10S) is a heterobifunctional PEG derivative. This compound features both a carboxyl group and a thiol group, making it suitable for diverse conjugation chemistries. It is primarily employed in chemical biology and synthesis, particularly for preparing advanced imaging agents and facilitating PEGylation strategies.
- IUPAC
- O-(2-Mercaptoethyl)-O′-(2-carboxyethy)heptaethylene glycol,PEG thiol acid
- Synonyms
- PEG thiol acid

Preparation of Near-Infrared Fluorochromes
This reagent is specifically utilised in the synthesis of near-infrared (NIR) fluorochromes. These fluorochromes are essential for advanced biological imaging techniques, enabling enhanced visualisation of biological processes.
Heterobifunctional PEGylation
The distinct reactive termini (carboxyl and thiol) allow for selective conjugation to different biomolecules or surfaces. This characteristic is valuable in PEGylation strategies to modify the properties of therapeutic proteins or nanoparticles.
Chemical Synthesis
As a versatile building block, it supports various chemical synthesis pathways requiring the introduction of a heptaethylene glycol spacer with dual functionality for complex molecular architectures.
| Molecular weight | 458.56 |
|---|---|
| Empirical formula | C19H38O10S |
| Assay | ≥95% (oligomer purity) |
| Storage temperature | −20°C |
| Application | Used to prepare near infrared fluorochromes for use in imaging.1 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol used for?
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This compound is used for preparing near-infrared fluorochromes for imaging and in various chemical synthesis applications, particularly for heterobifunctional PEGylation.
What are the CAS number and formula for O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol?
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The CAS number is 866889-02-3, and the empirical formula is C19H38O10S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥95% oligomer purity. This is a research-grade chemical and not represented as USP, BP, or EP.
What are the safety and handling considerations for this product?
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Users should wear eyeshields and gloves when handling this chemical. It has a WGK Germany classification of 3, indicating it is hazardous to water.
How is O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol packed, shipped, and exported?
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This chemical is typically stored at -20°C and is carefully packed and exported by Tech Serve Solutions according to international shipping regulations for fine chemicals.
How can I request a sample or a quote for this chemical?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via the website or direct inquiry.
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