NS 1619
NS 1619 (CAS: 153587-01-0), a fluorinated benzimidazolone derivative with the molecular formula C15H8F6N2O2 and a molecular weight of 362.23 g/mol, is a specialized chemical intermediate. It is primarily utilised in research settings for investigating ion channel function, particularly voltage-gated and monovalent ion channels. Its specific applications lie within cell biology and cell signaling studies, contributing to a deeper understanding of neurological processes.
- IUPAC
- 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one

Ion Channel Research
NS 1619 serves as a valuable tool in the study of ion channels, including voltage-gated and monovalent types. Its properties allow researchers to probe channel activity and modulation in cellular systems.
Cell Biology and Signaling
This compound is employed in cell biology research to investigate cellular signaling pathways. It aids in understanding the complex mechanisms governing cell function and response.
Neuroscience Studies
Due to its relevance to ion channels, NS 1619 finds application in neuroscience research, particularly in exploring the molecular basis of neuronal function and dysfunction.
| Molecular weight | 362.23 |
|---|---|
| Empirical formula | C15H8F6N2O2 |
| Form | powder |
| Colour | white |
| Solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.47 mg/mLethanol: soluble26.6 mg/mL0.1 M NaOH: soluble5.2 mg/mLDMSO: soluble5.3 mg/mLH2O: insoluble |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Kcnma1(16531)rat ... Kcnma1(83731) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NS 1619 used for?
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NS 1619 is used in research for investigating ion channel function, particularly voltage-gated and monovalent ion channels, within cell biology, cell signaling, and neuroscience studies.
What is the CAS number and molecular formula for NS 1619?
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The CAS number for NS 1619 is 153587-01-0, and its molecular formula is C15H8F6N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies NS 1619 as a research-grade chemical. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for NS 1619?
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NS 1619 is classified under WGK Germany 3. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling.
How is NS 1619 packed, shipped, and exported?
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NS 1619 is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for NS 1619?
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To request a sample or a quote for NS 1619, please contact our sales team through the website or by telephone.
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