NB001
NB001 (CAS 686301-48-4), a potent adenylyl cyclase activator with the molecular formula C12H20N6O and a molecular weight of 264.33 g/mol, is a valuable research tool in cell biology. It specifically targets adenylyl cyclase 1, playing a role in cellular signaling pathways. Available as a white to tan powder, NB001 is soluble in water and facilitates studies into cyclic nucleotide metabolism and G protein signaling.
- IUPAC
- 5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanol; HTS 09836
- Synonyms
- 5-[[2-(6-Amino-9H-purin-9-yl)ethyl]amino]-1-pentanolHTS 09836

Adenylyl Cyclase 1 Activation
NB001 is primarily utilised as an activator of adenylyl cyclase 1. This makes it an indispensable tool for researchers investigating cellular signalling pathways mediated by this enzyme.
Cell Signaling Research
This compound serves as a valuable reagent in studies focused on cell signalling mechanisms. Its ability to modulate adenylyl cyclase activity aids in understanding signal transduction cascades within cells.
Neuroscience Studies
Within neuroscience, NB001 can be applied to explore the role of adenylyl cyclase in neuronal function and signalling. Its impact on cyclic nucleotide metabolism is relevant for understanding neurological processes.
Cyclic Nucleotide Metabolism
Researchers can employ NB001 to investigate the metabolic pathways of cyclic nucleotides. Its action as an adenylyl cyclase activator directly influences intracellular cyclic AMP levels.
| Molecular weight | 264.33 |
|---|---|
| Empirical formula | C12H20N6O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to tan |
| Solubility | H2O: ≥24 mg/mL |
| Storage temperature | −20°C |
| Application | NB001 may be used in adenylyl cyclase 1-mediated cell signaling studies. |

Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is NB001 used for?
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NB001 is used for studies involving adenylyl cyclase 1-mediated cell signalling, neuroscience research, and investigating cyclic nucleotide metabolism.
What are the CAS number and molecular formula for NB001?
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The CAS number for NB001 is 686301-48-4, and its empirical formula (Hill notation) is C12H20N6O.
What grade and purity does Tech Serve Solutions supply for NB001?
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Tech Serve Solutions supplies NB001 with an assay of ≥98% by HPLC. This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should NB001 be handled safely?
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NB001 is classified as acutely toxic if swallowed (H301) and requires careful handling. Wear appropriate personal protective equipment, including gloves and eye protection, and avoid ingestion. Refer to the Safety Data Sheet for full handling and emergency procedures.
How is NB001 shipped and exported?
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NB001 is shipped and exported according to international regulations for hazardous materials, identified as UN 2811, Class 6.1, Packing Group III. Tech Serve Solutions ensures compliance with all relevant shipping and export requirements.
How can I request a sample or quote for NB001?
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To request a sample or a quotation for NB001, please contact our sales department via the website or email. Provide your contact details and the quantity required.
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