Naphthol AS-TR phosphate
Naphthol AS-TR phosphate (CAS 2616-72-0) is a chemical compound with the molecular formula C18H15ClNO5P and a molecular weight of 391.74 g/mol. It serves as a critical substrate in histochemical staining techniques. Its primary application lies in the accurate and reliable demonstration of both acid and alkaline phosphatase activities within biological tissues, making it an indispensable reagent for research and diagnostic laboratories.

Enzyme Substrate for Phosphatase Detection
Naphthol AS-TR phosphate is employed as a chromogenic substrate for the quantitative and qualitative determination of acid and alkaline phosphatase enzyme activities. Upon enzymatic cleavage, it yields a coloured precipitate, enabling visualisation of enzyme localisation in tissue sections.
Histochemical Staining
This compound is widely utilised in histochemistry for the specific staining of tissues to identify and study the distribution of phosphatase enzymes. It is a key reagent in protocols for immunohistochemistry and Western blotting procedures.
Biochemical Research
As a specialised biochemical reagent, Naphthol AS-TR phosphate supports research into enzyme kinetics, cellular metabolism, and diagnostic marker identification. Its reliable performance is crucial for obtaining consistent and reproducible experimental results in biological and medical research.
| Molecular weight | 391.74 |
|---|---|
| Empirical formula | C18H15ClNO5P |
| Storage temperature | −20°C |
| Application | Substrate for the histochemical demonstration of acid and alkaline phosphatase. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naphthol AS-TR phosphate primarily used for?
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Naphthol AS-TR phosphate (CAS 2616-72-0) is primarily used as a substrate for the histochemical demonstration of acid and alkaline phosphatase enzyme activities in biological tissues. It enables the visualisation of these enzymes through a coloured precipitate formed after enzymatic cleavage.
What is the CAS number and molecular formula for Naphthol AS-TR phosphate?
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The CAS number for Naphthol AS-TR phosphate is 2616-72-0. Its molecular formula is C18H15ClNO5P.
What grade and purity does Tech Serve Solutions supply for Naphthol AS-TR phosphate?
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Tech Serve Solutions supplies Naphthol AS-TR phosphate, typically as a research or technical grade material. The exact purity and assay are detailed in the product's Certificate of Analysis, and we do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the specifications.
What are the safety and handling precautions for Naphthol AS-TR phosphate?
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Naphthol AS-TR phosphate is classified with GHS07 symbol and a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used when handling. Ensure good ventilation. Refer to the Safety Data Sheet (SDS) for full details.
How is Naphthol AS-TR phosphate packed, shipped, and exported?
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Naphthol AS-TR phosphate is typically supplied in powder form. It is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions following all necessary regulatory and shipping guidelines for chemical substances.
How can I request a sample or quote for Naphthol AS-TR phosphate?
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To request a sample or obtain a quotation for Naphthol AS-TR phosphate, please contact our sales team directly through the contact details provided on the Tech Serve Solutions website or use the inquiry form associated with the product listing.
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