Naltrindole hydrochloride
Naltrindole hydrochloride (CAS: 111469-81-9), with the empirical formula C26H26N2O3 · HCl and a molecular weight of 450.96 g/mol, is a selective delta-opioid receptor antagonist. This off-white solid is commonly utilised in scientific research as a tool for investigating opioid receptor pharmacology. Its applications primarily lie within cell signalling and neuroscience research, aiding in the study of pain pathways and addiction mechanisms.
- IUPAC
- NTI hydrochloride

Opioid Receptor Research
Naltrindole hydrochloride serves as a selective antagonist for delta-opioid receptors (OPRD1). It is instrumental in dissecting the roles of different opioid receptor subtypes in physiological and pathological processes, including pain perception and the effects of addictive substances.
Neuroscience and Pharmacology Studies
This compound is a valuable reagent in neuroscience, enabling researchers to study the complex signalling pathways involving opioid receptors in the central nervous system. It aids in understanding neurotransmission and the development of novel therapeutic strategies.
Cell Biology Investigations
As a bioactive small molecule, Naltrindole hydrochloride is employed in cell biology to investigate cellular responses mediated by opioid receptors. Its use helps in characterising receptor function and downstream signalling events within various cell types.
| Molecular weight | 450.96 |
|---|---|
| Empirical formula | C26H26N2O3 · HCl |
| Form | solid |
| Colour | off-white |
| Solubility | methanol: soluble4.5 mg/mLH2O: soluble8 mg/mL |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... OPRD1(4985) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naltrindole hydrochloride used for?
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Naltrindole hydrochloride is primarily used as a selective delta-opioid receptor antagonist in scientific research, particularly in neuroscience and cell biology, to investigate opioid receptor pharmacology and related signalling pathways.
What is the CAS number and formula for Naltrindole hydrochloride?
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The CAS number for Naltrindole hydrochloride is 111469-81-9, and its empirical formula is C26H26N2O3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naltrindole hydrochloride as a technical/research grade solid. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated otherwise in the product specifications.
What are the safety and handling precautions for Naltrindole hydrochloride?
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When handling Naltrindole hydrochloride, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is Naltrindole hydrochloride packed, shipped, and exported?
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Naltrindole hydrochloride is supplied as an off-white solid, typically stored at -20°C. Tech Serve Solutions adheres to all relevant regulations for the packing, shipping, and export of chemicals globally.
How can I request a sample or quote for Naltrindole hydrochloride?
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To request a sample or a quote for Naltrindole hydrochloride, please contact our sales department through the website or by calling our dedicated customer service line.
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