N-Methyl-L-aspartic acid

CAS 4226-18-0C5H9NO4Biochemicals & Reagents

N-Methyl-L-aspartic acid (CAS 4226-18-0) is a modified amino acid with the molecular formula C5H9NO4 and a molecular weight of 147.13 g/mol. It is recognised for its role as an agonist for NMDA receptors, influencing excitatory neurotransmission in the central nervous system. This compound is valuable in neuroscientific research for investigating synaptic plasticity and excitotoxicity.

IUPAC: (S)-2-(Methylamino)succinic acid
Synonyms: (S)-2-(Methylamino)succinic acid

Email us

N-Methyl-L-aspartic acid (C5H9NO4) — chemical structure, CAS 4226-18-0; Life Science, fine chemical supplied by Tech Serve Solutions

Amino AcidsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyModified Amino Acids More...

01 /Applications

Neuroscience Research Tool

N-Methyl-L-aspartic acid is widely used in neuroscience to study the function and regulation of N-methyl-D-aspartate (NMDA) receptors. It serves as a specific agonist to probe receptor activation and its downstream effects on neuronal signalling.

Investigating Synaptic Plasticity

As a potent NMDA receptor agonist, this compound aids in research related to long-term potentiation (LTP) and long-term depression (LTD), key mechanisms underlying learning and memory.

Excitotoxicity Studies

It is employed to model and understand excitotoxicity, a process where neuronal damage occurs due to overstimulation by excitatory neurotransmitters, which is relevant to various neurological disorders.

02 /Properties

Molecular weight	147.13
Empirical formula	C5H9NO4

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4226-18-0

MDL number

MFCD00069561

Beilstein registry

2437887

05 /Additional specifications

Gene Information	rat ... Gria1(50592), Grik1(29559), Grin2a(24409)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is N-Methyl-L-aspartic acid used for?

N-Methyl-L-aspartic acid is primarily used as a research tool in neuroscience to study the function and regulation of NMDA receptors, investigate synaptic plasticity, and understand excitotoxicity.

What are the CAS number and formula for N-Methyl-L-aspartic acid?

The CAS number for N-Methyl-L-aspartic acid is 4226-18-0, and its molecular formula is C5H9NO4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies N-Methyl-L-aspartic acid as a research-grade chemical. The specific purity is detailed on the Certificate of Analysis. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.

What are the safety and handling precautions for N-Methyl-L-aspartic acid?

Handling N-Methyl-L-aspartic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It carries a WGK Germany classification of 3, indicating a higher hazard.

How is N-Methyl-L-aspartic acid packed and shipped?

N-Methyl-L-aspartic acid is carefully packed to ensure safe transport and is exported globally by Tech Serve Solutions according to all relevant regulations.