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N-Methoxy-N-methyl-2,2,2-trifluoroacetamide

CAS 104863-67-4C4H6F3NO2Organic Building Blocks

N-Methoxy-N-methyl-2,2,2-trifluoroacetamide (CAS: 104863-67-4) is a fluorinated organic compound with the molecular formula C4H6F3NO2 and a molecular weight of 157.09 g/mol. It serves as a valuable building block and intermediate in organic synthesis, particularly for introducing trifluoroacetyl groups. This compound is typically supplied at a purity of 98%, suitable for research and chemical synthesis applications. Its chemical properties make it a useful reagent in various chemical transformations.

IUPAC
N-Methyl-N-methoxytrifluoroacetamide
Synonyms
104863-67-4C4H6F3NO2N-Methoxy-N-methyltrifluoroacetamideN-Methyl-N-methoxytrifluoroacetamide
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N-Methoxy-N-methyl-2,2,2-trifluoroacetamide (C4H6F3NO2) — chemical structure, CAS 104863-67-4; Chemistry, fine chemical supplied by Tech Serve Solutions
AmidesBuilding BlocksC2 to C7Carbonyl CompoundsChemical Synthesis
01 /Applications

Organic Synthesis Intermediate

N-Methoxy-N-methyl-2,2,2-trifluoroacetamide acts as a key intermediate in the synthesis of complex organic molecules. Its trifluoroacetyl moiety can be readily transferred in various chemical reactions.

Fluorination Reagent

This compound can be employed as a reagent for introducing trifluoromethyl groups or trifluoroacetyl functionalities into organic structures. This is crucial for developing novel pharmaceuticals and agrochemicals.

Building Block for Specialty Chemicals

As an organic building block, it facilitates the construction of specialised chemical entities. Its unique structure is leveraged in academic and industrial research laboratories for creating new chemical entities.

02 /Properties
Molecular weight157.09
Empirical formulaC4H6F3NO2
Assay98%
Boiling point53 °C/30 mmHg(lit.)
Density1.299 g/mL at 25 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H301Toxic if swallowed
  • H319Causes serious eye irritation

Precautionary statements

  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point47 °C / 116.6 °F
Transport (UN / ADR)UN 1992 3/PG 3
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)10-25-36
Safety statements (S)16-26-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
104863-67-4
MDL number
MFCD00077565
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Methoxy-N-methyl-2,2,2-trifluoroacetamide used for?

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N-Methoxy-N-methyl-2,2,2-trifluoroacetamide is primarily used as an intermediate and building block in organic synthesis, particularly for introducing trifluoroacetyl groups into other molecules. It is valuable in the development of pharmaceuticals and agrochemicals.

What is the CAS number and formula for N-Methoxy-N-methyl-2,2,2-trifluoroacetamide?

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The CAS number for N-Methoxy-N-methyl-2,2,2-trifluoroacetamide is 104863-67-4, and its empirical formula is C4H6F3NO2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies N-Methoxy-N-methyl-2,2,2-trifluoroacetamide with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should N-Methoxy-N-methyl-2,2,2-trifluoroacetamide be handled safely?

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N-Methoxy-N-methyl-2,2,2-trifluoroacetamide is classified as Danger (GHS02, GHS06) with hazards H226 (Flammable liquid and vapour) and H301 (Toxic if swallowed). It also carries H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment including eyeshields, face shields, gloves, and a suitable respirator. Ensure good ventilation and avoid ignition sources. Store in a cool, well-ventilated place, away from heat and ignition sources.

How is N-Methoxy-N-methyl-2,2,2-trifluoroacetamide packed and shipped?

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This product is typically packed in accordance with international shipping regulations for hazardous materials. As a flammable and toxic liquid, it is shipped as UN 1992, 3/PG 3. We export globally, adhering to all relevant transport and customs requirements.

How can I request a sample or quote for N-Methoxy-N-methyl-2,2,2-trifluoroacetamide?

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To request a sample or a quote, please contact our sales department through the website or by phone. Provide the product name, CAS number, and the quantity required for a prompt response.

Need N-Methoxy-N-methyl-2,2,2-trifluoroacetamide in a specific grade or volume?