N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide

CAS 143503-03-1C20H16N2O5Biochemicals & Reagents

N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide (CAS: 143503-03-1) is a specialised chemical reagent. Utilising its reactive maleimide group, it selectively labels proteins via their sulfhydryl groups, forming fluorescent derivatives. The dimethoxyphthalimidyl moiety provides a high fluorescence intensity, making it valuable for various biochemical and research applications where precise labelling and detection are critical. This compound is supplied by TSS with a minimum assay of 97.0% (HPLC).

IUPAC: DPM
Synonyms: C20H16N2O5DPM

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N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide (C20H16N2O5) — chemical structure, CAS 143503-03-1; Life Science, fine chemical supplied by Tech Serve Solutions

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01 /Applications

Protein Fluorescence Labelling

N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide is employed for the selective fluorescence labelling of proteins. It reacts with sulfhydryl groups on proteins to create fluorescent conjugates.

Thiol Compound Derivatisation

This reagent reacts with thiol compounds to produce fluorescent derivatives. The dimethoxyphthalimidyl group offers enhanced fluorescence intensity compared to unsubstituted analogues.

Biochemical Research

Used as a fluorescent probe in biochemical research for the detection and analysis of specific molecular targets, particularly those containing thiol functionalities.

02 /Properties

Empirical formula	C20H16N2O5
Assay	≥97.0% (HPLC)
Application	N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide (DPM) is used to fluorescence label proteins via their sulfhydryl groups. Nonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the non substituted phthalimidyl group.

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

143503-03-1

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide used for?

N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide is used to fluorescence label proteins via their sulfhydryl groups and to create fluorescent derivatives of thiol compounds. Its dimethoxyphthalimidyl group provides high fluorescence intensity.

What is the CAS number and formula for N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide?

The CAS number is 143503-03-1. The empirical formula is C20H16N2O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide with a minimum assay of 97.0% (HPLC). This product is intended for research and laboratory use.

What are the safety and handling recommendations for this chemical?

Users should wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The product has a WGK rating of 3 in Germany, indicating it is hazardous to water.

How is this chemical supplied and exported?

Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide, adhering to all relevant export regulations.

How can I request a quote or sample?

To request a quote or sample of N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide, please contact our sales department via the TSS website or direct email.