N-(2,6-Dimethylphenyl)chloroacetamide
N-(2,6-Dimethylphenyl)chloroacetamide (CAS: 1131-01-7) is a fine chemical compound with the molecular formula ClCH₂CONHC₆H₃(CH₃)₂ and a molecular weight of 197.66 g/mol. This organic building block is primarily utilised in chemical synthesis and serves as a key reagent in analytical chemistry. Its properties make it valuable for specific applications requiring precise chemical interactions and determinations.
- IUPAC
- 1-Chloroacetylamino-2,6-dimethylbenzene,2-Chloro-2′,6′-acetoxylidide,2-Chloro-2′,6′-dimethylacetanilide,2-Chloro-N-(2,6-dimethylphenyl)acetamide,N-(2,6-Dimethylphenyl)-2-chloroacetamide,N-(2,6-Xylyl)chloroacetamide,N-Chloroacetyl-2,6-dimethylaniline,Chloroacetamido-2,6-xylidine
- Synonyms
- ClCH2CONHC6H3(CH3)21-Chloroacetylamino-2,6-dimethylbenzene2-Chloro-2′,6′-acetoxylidide2-Chloro-2′,6′-dimethylacetanilide2-Chloro-N-(2,6-dimethylphenyl)acetamideN-(2,6-Dimethylphenyl)-2-chloroacetamideN-(2,6-Xylyl)chloroacetamideN-Chloroacetyl-2,6-dimethylanilineChloroacetamido-2,6-xylidine

Analytical Reagent
N-(2,6-Dimethylphenyl)chloroacetamide has been employed in sophisticated analytical methods, such as the simultaneous determination of tocainide enantiomers in blood plasma using gas-liquid chromatography with electron-capture detection.
Organic Synthesis Intermediate
As a functionalised amide, this compound serves as a versatile building block in organic synthesis. It can be incorporated into larger molecules or used to introduce specific chemical functionalities during multi-step syntheses.
Research and Development
This chemical is utilised in research laboratories for exploring new synthetic pathways and developing novel compounds. Its defined structure and reactivity make it suitable for various research purposes.
| Molecular weight | 197.66 |
|---|---|
| Linear formula | ClCH2CONHC6H3(CH3)2 |
| Assay | 99% |
| Application | N-(2,6-Dimethylphenyl)chloroacetamide (2-chloro-2′,6′-acetoxylidide) was used in simultaneous determination of the enantiomers of tocainide in blood plasma by gas-liquid chromatography with electron-capture detection1. |
| Melting point | 150-151 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary applications of N-(2,6-Dimethylphenyl)chloroacetamide?
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N-(2,6-Dimethylphenyl)chloroacetamide is used in analytical chemistry for methods such as determining tocainide enantiomers in blood plasma, and it also functions as a building block in organic synthesis and for general research purposes.
What is the CAS number and molecular formula for N-(2,6-Dimethylphenyl)chloroacetamide?
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The CAS number is 1131-01-7, and the molecular formula is ClCH₂CONHC₆H₃(CH₃)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(2,6-Dimethylphenyl)chloroacetamide with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should N-(2,6-Dimethylphenyl)chloroacetamide be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves. Avoid breathing dust. This compound is classified as irritating to the skin, eyes, and respiratory system (H315, H319, H335).
How is N-(2,6-Dimethylphenyl)chloroacetamide packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging and shipping details for N-(2,6-Dimethylphenyl)chloroacetamide are available upon request, adhering to international shipping regulations.
How can I request a sample or a quote for N-(2,6-Dimethylphenyl)chloroacetamide?
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To request a sample or a quote, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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