Methyl chlorodifluoroacetate
Methyl chlorodifluoroacetate (CAS: 1514-87-0), with the linear formula ClF2CCOOCH3 and a molecular weight of 144.50 g/mol, is a halogenated ester. This compound is primarily utilised as a versatile building block and reagent in organic synthesis. Its specific chemical properties make it valuable for introducing fluorinated moieties into more complex molecules across various chemical research and development applications.

Organic Synthesis Reagent
Methyl chlorodifluoroacetate serves as a key reagent in the synthesis of novel organic compounds. It is particularly useful for the introduction of difluoromethyl or related fluorinated groups into target molecules, offering pathways to new pharmaceuticals and agrochemicals.
Fluorinated Building Block
As a valuable building block, this ester is employed in the construction of more complex fluorinated structures. Its reactivity allows for diverse chemical transformations, contributing to the development of advanced materials and fine chemicals.
Research and Development
This compound is frequently used in academic and industrial research laboratories for exploring new synthetic methodologies and creating innovative chemical entities. Its availability supports exploratory chemical studies.
| Molecular weight | 144.50 |
|---|---|
| Linear formula | ClF2CCOOCH3 |
| Assay | 99% |
| Grade | puriss. |
| Boiling point | 79-81 °C(lit.) |
| Density | 1.37 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.349(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 19 °C / 66.2 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl chlorodifluoroacetate used for?
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Methyl chlorodifluoroacetate (CAS: 1514-87-0) is used as a versatile building block and reagent in organic synthesis, particularly for introducing fluorinated groups into molecules for research and development in areas like pharmaceuticals and materials science.
What are the CAS number and formula for Methyl chlorodifluoroacetate?
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The CAS number for Methyl chlorodifluoroacetate is 1514-87-0 and its linear formula is ClF2CCOOCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl chlorodifluoroacetate at a purity of 99% (puriss. grade). We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Methyl chlorodifluoroacetate be handled safely?
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Methyl chlorodifluoroacetate is a flammable liquid and causes severe skin burns and eye damage. Handle with extreme caution in a well-ventilated area, wearing appropriate protective equipment including gloves, eye protection, and protective clothing. Refer to the Safety Data Sheet for detailed handling and emergency procedures.
How is Methyl chlorodifluoroacetate packed and exported?
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Methyl chlorodifluoroacetate is packed and shipped in compliance with international regulations for hazardous materials, including UN 2924 classification. TSS is experienced in global export of such chemicals.
How can I request a sample or quote for Methyl chlorodifluoroacetate?
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To request a sample or a quotation for Methyl chlorodifluoroacetate, please contact the Tech Serve Solutions sales team through our website or by phone, referencing the product name and CAS number.
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