Methazolamide
Methazolamide (CAS: 554-57-4; C5H8N4O3S2) is a white to beige powder with a molecular weight of 236.27 g/mol. This compound is known for its activity as a carbonic anhydrase inhibitor. It is primarily used in laboratory research settings for biochemical studies, particularly in investigations involving enzyme kinetics and the physiological roles of carbonic anhydrase.
- IUPAC
- 5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamide,N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene) acetamide,L 584601,N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide
- Synonyms
- 5-Acetylimino-4-methyl-·2-1,3,4-thiadiazoline-2-sulfonamideN-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)acetamideL 584601N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide

Carbonic Anhydrase Inhibition Research
Methazolamide serves as a valuable tool in research laboratories for studying the function and inhibition of carbonic anhydrase enzymes. Its specific inhibitory properties allow for detailed investigations into enzyme mechanisms and physiological processes regulated by these enzymes.
Biochemical Studies
As a biochemical reagent, Methazolamide is employed in various in vitro experiments to understand cellular processes. Researchers utilize it to explore the effects of carbonic anhydrase modulation on biological systems and pathways.
Enzyme Inhibitor Studies
This compound is classified as an enzyme inhibitor, making it suitable for research focused on enzyme structure-activity relationships and the development of novel therapeutic agents targeting enzyme pathways.
| Molecular weight | 236.27 |
|---|---|
| Empirical formula | C5H8N4O3S2 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble20 mg/mL, clear |
| Storage temperature | 2-8°C |
| Melting point | 208 °C (dec.)(lit.) |


Hazard statements
- H302Harmful if swallowed
- H351Suspected of causing cancer
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-40 |
| Safety statements (S) | 22-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Storage Condition | protect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methazolamide used for?
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Methazolamide is primarily used in laboratory research as a carbonic anhydrase inhibitor for biochemical studies and investigations into enzyme kinetics.
What is the CAS number and formula for Methazolamide?
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The CAS number for Methazolamide is 554-57-4, and its empirical formula is C5H8N4O3S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methazolamide with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should Methazolamide be handled and stored?
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Methazolamide is classified as harmful if swallowed, in contact with skin, or if inhaled (H302 + H312 + H332) and suspected of causing cancer (H351). It should be handled with appropriate personal protective equipment (P280) and stored at 2-8°C, protected from light.
How is Methazolamide packed and shipped by TSS?
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Methazolamide is exported by Tech Serve Solutions in appropriate packaging designed to maintain its integrity during transit. Specific packaging details can be provided upon request.
How can I request a quote or sample for Methazolamide?
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To request a quote or a sample of Methazolamide, please contact the Tech Serve Solutions sales team through our website or by phone.
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