Mefenamic acid
Mefenamic acid (CAS 61-68-7, C15H15NO2) is a non-steroidal anti-inflammatory drug (NSAID) with a molecular weight of 241.29 g/mol. It is recognised for its ability to circumvent MRP-mediated multidrug resistance. This compound is particularly noted for its synergistic effect in potentiating the cytotoxicity of certain chemotherapy agents, making it a valuable research chemical in cancer biology and drug development studies.
- IUPAC
- 2-[(2,3-Dimethylphenyl)amino]benzoic acid,N-(2,3-Xylyl)anthranilic acid
- Synonyms
- 2-[(2,3-Dimethylphenyl)amino]benzoic acidN-(2,3-Xylyl)anthranilic acid
NSAID Research
As a non-steroidal anti-inflammatory drug, Mefenamic acid serves as a reference compound in research exploring inflammatory pathways and pain mechanisms.
Chemotherapy Resistance Studies
Mefenamic acid is utilised in research to investigate and overcome multidrug resistance (MRP-mediated) in cancer cells, specifically its ability to potentiate the effects of anthracyclines and other cytotoxic agents.
Drug Transport Research
The compound is employed in studies focusing on drug efflux pumps and transporters, particularly those involved in multidrug resistance, aiding in the understanding of drug disposition and efficacy.
| Molecular weight | 241.29 |
|---|---|
| Empirical formula | C15H15NO2 |
| Application | An NSAID. Circumvents MRP-mediated multidrug resistance. Specifically and significantly potentiates the cytotoxicity of anthracyclines (doxorubicin, daunorubicin and epirubicin), as well as teniposide, VP-16 and vincristine. |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Mefenamic acid used for?
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Mefenamic acid is used in research as an NSAID and to investigate the circumvention of MRP-mediated multidrug resistance, where it potentiates the cytotoxicity of certain chemotherapy agents.
What is the CAS number and formula for Mefenamic acid?
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The CAS number for Mefenamic acid is 61-68-7 and its empirical formula is C15H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Mefenamic acid for research purposes. The specific assay and purity are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should Mefenamic acid be handled safely?
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Mefenamic acid is classified with GHS07 and a signal word of 'Warning', with hazard statement H302 (Harmful if swallowed). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves.
Is Mefenamic acid a controlled substance?
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The provided data does not indicate that Mefenamic acid is a controlled substance.
How is Mefenamic acid packed and shipped?
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Tech Serve Solutions packs and ships Mefenamic acid according to standard chemical handling and export regulations to ensure product integrity and safety during transit.
How can I request a sample or quote for Mefenamic acid?
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To request a sample or a quote for Mefenamic acid, please contact our sales team through the website or by calling us directly.
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