Lithium citrate tribasic tetrahydrate
Lithium citrate tribasic tetrahydrate (CAS 6080-58-6) is a chemical compound with the linear formula HOC(COOLi)(CH<sub>2</sub>COOLi)<sub>2</sub> · 4H<sub>2</sub>O and a molecular weight of 281.98 g/mol. It is supplied at ≥99.5% purity. This compound is recognised for its utility as a potential therapeutic agent for Canavan disease, an inherited neurological disorder. It is also categorised under BioUltra Buffers, Biochemicals and Reagents, Biological Buffers, and Chelators, indicating its broader applications in biochemical research and laboratory settings.
- IUPAC
- Citric acid trilithium salt,Trilithium citrate tetrahydrate
- Synonyms
- Citric acid trilithium saltTrilithium citrate tetrahydrate

Therapeutic Potential for Canavan Disease
Lithium citrate tribasic tetrahydrate has demonstrated utility as a potential therapeutic agent for Canavan disease, a rare genetic disorder affecting brain development. Its application stems from its potential to address aspartoacylase deficiency or aminoacylase 2 deficiency.
Buffer Solutions
As a component within the 'Biological Buffers' and 'BioUltra Buffers' categories, this compound can be utilised in the formulation of buffer solutions. Its buffering capacity is indicated by its pH range of 8.0-9.5 in a 1M aqueous solution.
Chelating Agent
Included in the 'Chelators' classification, lithium citrate tribasic tetrahydrate possesses properties that allow it to bind with metal ions. This characteristic is valuable in various laboratory and industrial applications where metal ion control is necessary.
Biochemical Reagent
Within the broader 'Biochemicals and Reagents' group, this compound serves as a valuable reagent for research and development in biochemistry. Its defined specifications and purity make it suitable for sensitive experimental protocols.
| Molecular weight | 281.98 |
|---|---|
| Linear formula | HOC(COOLi)(CH2COOLi)2 · 4H2O |
| Assay | ≥99.5% (NT) |
| Solubility | H2O: soluble1 M at 20 °C, clear, colorless |
| pH | 8.0-9.5 (25 °C, 1 M in H2O) |
| Impurities tested | insoluble matter, passes filter test |
| Application | Lithium citrate is useful as a potential therapeutic for Canavan disease due to aspartoacylase deficiency or aminoacylase 2 deficiency. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Uv Absorption | λ: 260 nm Amax: 0.040λ: 280 nm Amax: 0.016 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lithium citrate tribasic tetrahydrate used for?
+
Lithium citrate tribasic tetrahydrate is primarily recognised for its potential therapeutic application in managing Canavan disease. It also serves as a reagent in biochemical research, can be used in the formulation of biological buffer solutions, and functions as a chelating agent.
What are the CAS number and formula for Lithium citrate tribasic tetrahydrate?
+
The CAS number for Lithium citrate tribasic tetrahydrate is 6080-58-6. Its linear formula is HOC(COOLi)(CH<sub>2</sub>COOLi)<sub>2</sub> · 4H<sub>2</sub>O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Lithium citrate tribasic tetrahydrate with an assay of ≥99.5% (NT). TSS does not represent this product as USP, BP, or EP grade unless explicitly stated in the product documentation.
What are the safety and handling precautions for Lithium citrate tribasic tetrahydrate?
+
This compound is classified as a GHS07 (Warning) substance, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation.
How is Lithium citrate tribasic tetrahydrate packed and shipped?
+
Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details are available upon request and are tailored to comply with international regulations for the safe transport of chemical substances.
How can I request a sample or quote for Lithium citrate tribasic tetrahydrate?
+
To request a sample or a quotation for Lithium citrate tribasic tetrahydrate, please contact our sales department via the website or through the provided contact information. Specify the quantity and delivery location for an accurate response.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis